Accommodative function in rhesus monkeys: effects of aging and calorie restriction [0.03%]
老龄和卡路里限制对恒河猴调节性功能的影响
J A Mattison,M A Croft,D B Dahl et al.
J A Mattison et al.
Numerous degenerative changes in the visual system occur with age, including a loss of accommodative function possibly related to hardening of the lens or loss of ciliary muscle mobility. The rhesus monkey is a reliable animal model for stu...
Dietary supplementation with fruit polyphenolics ameliorates age-related deficits in behavior and neuronal markers of inflammation and oxidative stress [0.03%]
水果多酚类膳食补充剂可改善与年龄相关的炎症和氧化应激的神经元标志物及行为缺陷
Barbara Shukitt-Hale,Rachel L Galli,Vanessa Meterko et al.
Barbara Shukitt-Hale et al.
Dietary supplementation with fruit or vegetable extracts can ameliorate age-related declines in measures of learning, memory, motor performance, and neuronal signal transduction in a rat model. To date, blueberries have proved most effectiv...
Caloric restriction versus drug therapy to delay the onset of aging diseases and extend life [0.03%]
限制卡路里摄取与用药：推迟衰老及相关疾病的发生和延长寿命
Arthur V Everitt,George S Roth,David G Le Couteur et al.
Arthur V Everitt et al.
There are two firmly established methods of prolonging life. Calorie restriction (CR) using nutrient-rich diets to prolong life in lower animals, and life saving medications in humans to delay the development of the major diseases of middle...
Assessment of nutritional interventions for modification of age-associated cognitive decline using a canine model of human aging [0.03%]
利用犬类老化模型评估营养干预在调节与年龄相关的认知衰退方面的效果
Joseph A Araujo,Christa M Studzinski,Elizabeth Head et al.
Joseph A Araujo et al.
The present review focuses on the utility of a canine model in evaluating nutritional interventions for age-related cognitive dysfunction. Aged dogs demonstrate progressive cognitive decline with concurrent amyloid-beta pathology that paral...
The diet restriction paradigm: a brief review of the effects of every-other-day feeding [0.03%]
隔日进食的限制饮食模式-简短综述
R Michael Anson,Bruce Jones,Rafael de Cabod
R Michael Anson
It has been known since the early 1900s that restriction of dietary intake relative to the ad libitum (AL) level increases stress resistance, cancer resistance, and longevity in many species. Studies investigating these phenomena have used ...
Lifelong vitamin E intake retards age-associated decline of spatial learning ability in apoE-deficient mice [0.03%]
维生素E终生摄取延缓apoE基因缺陷小鼠空间学习能力的年龄相关性减退
Shelley R McDonald,Michael J Forster
Shelley R McDonald
The potential for lifelong vitamin E supplementation to delay age-associated cognitive decline was tested in apoE-deficient and wild-type C57BL/6 mice. Beginning at eight weeks of age, the mice were maintained on a control diet or diets sup...
Do personality characteristics predict longevity? Findings from the Tokyo Centenarian Study [0.03%]
人格特征能预测长寿吗？东京百岁老人研究的结果告诉你
Y Masui,Y Gondo,H Inagaki et al.
Y Masui et al.
To explore whether personality influences longevity we examined the personality characteristics of centenarians. We developed a new method that compares an actual personality test score for centenarians with a predicted test score for a 100...
Peter Martin,Grace da Rosa,Ilene C Siegler et al.
Peter Martin et al.
Centenarians are thought of as unique and exceptional survivors. This study evaluated specific personality traits and configurations of traits among participants of the Georgia Centenarian Study. Two hundred and eighty five centenarians and...
Dietary differences between centenarians residing in communities and in skilled nursing facilities: the Georgia Centenarian Study [0.03%]
社区居住和专业护理机构中的百岁老人之间的饮食差异：佐治亚州百岁老人研究
Mary Ann Johnson,Adam Davey,Dorothy B Hausman et al.
Mary Ann Johnson et al.
The purpose of this study was to examine the dietary habits among centenarians residing in community settings (n=105) and in skilled nursing facilities (n=139). The sample was a population-based multi-ethnic sample of adults aged 98 years a...
Genetic determinants of exceptional human longevity: insights from the Okinawa Centenarian Study [0.03%]
基因决定子与人类长寿：来自冲绳百岁老人研究的见解
D Craig Willcox,Bradley J Willcox,Wen-Chi Hsueh et al.
D Craig Willcox et al.
Centenarians represent a rare phenotype appearing in roughly 10-20 per 100,000 persons in most industrialized countries but as high as 40-50 per 100,000 persons in Okinawa, Japan. Siblings of centenarians in Okinawa have been found to have ...