Three layer functional model and energy exchange concept of aging process [0.03%]
衰老过程的三层功能模型和能量交换概念
Valery Chuprin,William Mihajlovic
Valery Chuprin
Relying on a certain degree of abstraction, we can propose that no particular distinction exists between animate or living matter and inanimate matter. While focusing attention on some specifics, the dividing line between the two can be dra...
You don't need a weatherman: famines, evolution, and intervention into aging [0.03%]
你不必做气象预报员：饥荒、进化与干预衰老
Michael J Rae
Michael J Rae
Calorie restriction (CR) is the most robust available intervention into biological aging. Efforts are underway to develop pharmaceuticals that would replicate CR's anti-aging effects in humans ("CR mimetics"), on the assumption that the lif...
Sequestration of p27 within the cytoplasm of cardiac myocytes in chronic ischemic heart disease: pathogenic implications for ischemic cardiomyopathy [0.03%]
缺血性心脏病心肌细胞胞浆内p27聚集的病理意义
Mark A Smith,Xiongwei Zhu,Hyoung-Gon Lee et al.
Mark A Smith et al.
A number of recent studies have suggested that cardiac myocytes, previously considered post-mitotic, re-enter the cell cycle and possess the ability to proliferate with certain pathogenic stimuli. To study this further, we examined cellular...
Design for a study to determine optimal dosage of ascorbic acid and alpha-tocopherol in humans [0.03%]
关于确定人体维生素C和维生素E最佳用量的研究设计
Leta R Moser,Alfred B Ordman
Leta R Moser
Some clinical trials of vitamins C and E have neglected important design features. Our objective was to demonstrate a detailed design that includes essential elements for an effective study of these vitamins in vivo. While taking 400 IU (in...
Huber R Warner
Huber R Warner
The first 10 years of NIA's existence were characterized by funding for descriptive and discovery research, as the field had not yet come of age. As Couzin expressed it in the July 1, 2005 issue of Science, "Just 2 or 3 decades ago, researc...
The American Aging Association honors Huber R. Warner, PhD., Retiring Associate Director, National Institute on Aging [0.03%]
美国老年协会授予退休的国立老龄研究所副主任Huber R. Warner博士荣誉奖
George M Martin
George M Martin
On behalf of American Aging Association and his many biogerontological colleagues, the author thanks Huber R. Warner for his 21 years of exemplary service at the National Institute on Aging (NIA). In so honoring Dr. Warner, we also honor hi...
Reproduction and migration in relation to senescence in the barn swallow Hirundo rustica: A study of avian 'centenarians' [0.03%]
关于家燕种群迁移与衰老的研究——以“百岁”鸟类为例
Anders Pape Møller,Florentino de Lope,Nicola Saino
Anders Pape Møller
A. P. Moller, F. de Lope and N. Saino: Reproduction and migration in relation to senescence in the barn swallow Hirundo rustica: A study of avian 'centenarians'. Senescence reflects the decrease in age-dependent residual reproductive value,...
Age-related differences in nest defense in common terns: Relationship to other life-history parameters [0.03%]
普通燕鸥的筑巢习性与其生命周期参数的关系研究——以亲鸟驱赶异种鸟类的行为为观察点的研究
Jennifer Pearson,Ian C T Nisbet,Mary Ann Ottinger
Jennifer Pearson
The Common Tern (Sterno hirundo) is a long-lived colonial nesting seabird. Previous studies have shown that chick growth and fledging success vary with age of the parental pair and with laying date, with older parents and those nesting earl...
Barney A Schlinger,Colin J Saldanha
Barney A Schlinger
Songbirds perform some remarkable feats of memory, including forming memories for songs and for complex spatial features of their environments. Research into the neural and hormonal control of these behaviors reveals discrete circuits that ...
Avian immunosenescence [0.03%]
禽类免疫衰老
Emma T Lavoie
Emma T Lavoie
Immunosenescence, the aging of the immune system, is well studied in humans. Mammalian immune systems become less capable of fighting pathogens and individuals become more susceptible to infection and cancer in their elder years. Little is ...