Protein and lipid oxidative damage and complex I content are lower in the brain of budgerigar and canaries than in mice. Relation to aging rate [0.03%]
虎皮鹦鹉和 канариус鸟脑中的蛋白质和脂质氧化损伤及NADH脱氢酶(I)含量均低于小鼠神经系统衰老速度方面的研究关系
Reinald Pamplona,Manuel Portero-Otín,Alberto Sanz et al.
Reinald Pamplona et al.
What are the mechanisms determining the rate of animal aging? Of the two major classes of endothermic animals, bird species are strikingly long-lived compared to mammals of similar body size and metabolic rate. Thus, they are ideal models t...
Telomerase gene expression in the chicken: Telomerase RNA (TR) and reverse transcriptase (TERT) transcript profiles are tissue-specific and correlate with telomerase activity [0.03%]
家鸡端粒酶基因表达：端粒酶RNA（TR）和逆转录酶（TERT）转录谱具有组织特异性并与端粒酶活性相关
Thomas H O&#x;Hare,Mary E Delany
Thomas H O&#x;Hare
Telomerase is the specialized enzyme which replicates the telomeres, thus maintaining the integrity of the chromosome ends; in absence of enzyme activity telomere lengths decrease, ultimately impacting genome stability. In this study, we ex...
Meetings report 2005 [0.03%]
2005年会议报告摘要
Editorial board
Editorial board
Stephanie Jemielity,Michel Chapuisat,Joel D Parker et al.
Stephanie Jemielity et al.
Aging is a fascinating, albeit controversial, chapter in biology. Few other subjects have elicited more than a century of ever-increasing scientific interest. In this review, we discuss studies on aging in social insects, a group of species...
Understanding and treating neurodegeneration: insights from the flies [0.03%]
理解并治疗神经退行性疾病：果蝇中的新认识和新策略
Bingwei Lu
Bingwei Lu
Drosophila has recently emerged as a model system for studying mechanisms of neurodegeneration. Genetic models for most of the major neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), polyglutamine dis...
Gordon J Lithgow,Matthew S Gill,Anders Olsen et al.
Gordon J Lithgow et al.
Morris Waskar,Yishi Li,John Tower
Morris Waskar
Accumulating evidence suggests that with time human stem cells may become defective or depleted, thereby contributing to aging and aging-related diseases. Drosophila provides a convenient model system in which to study stem cell aging. The ...
Ronny Haenold,D Mokhtar Wassef,Stefan H Heinemann et al.
Ronny Haenold et al.
The last two decades brought remarkable insight into the nature of normal aging in multicellular organisms. However, we are still far away from realizing extension of maximum lifespan in humans. An important modulator of lifespan is oxidati...
Genetic approaches to study aging in Drosophila melanogaster [0.03%]
果蝇(Drosophila melanogaster)的遗传学研究方法及其在衰老研究中的应用
Luc Poirier,Laurent Seroude
Luc Poirier
The process of aging can be described as a progressive decline in an organism's function that invariably results in death. This decline results from the activities of intrinsic genetic factors within an organism. The relative contributions ...
Meeting report 2004 [0.03%]
2004年会议报告摘要
Editorial board
Editorial board