Reducing penicillin allergy mislabelling: A one-day structured training program improves nurses' knowledge and self-reported confidence in allergy assessment and skin testing [0.03%]
降低青霉素过敏误标记：一项为期一天的结构化培训计划可改善护士对过敏评估和皮试的信心与知识水平
Xinyu Duan,Weihong Shi,Jinxian Huang et al.
Xinyu Duan et al.
Background: Penicillins are the most commonly prescribed antibiotics; however, penicillin allergy (PA) labels are highly prevalent and often inaccurate, leading to suboptimal antibiotic selection use. In Mainland China, P...
A multicenter study of crisaborole use in pediatric patients with atopic dermatitis in real-world setting in Thailand [0.03%]
泰国真实世界环境中克萨波罗尔治疗儿童特应性皮炎的多中心研究
Susheera Chatproedprai,Nootchanard Rujimethapass,Patawee Na Bangxang et al.
Susheera Chatproedprai et al.
Background: Increasing evidence supports the efficacy of crisaborole in atopic dermatitis (AD). Ethnic differences in AD endotypes may influence treatment outcomes, while data in Southeast Asian children remain limited. ...
Evaluation of diagnostic approach and clinical outcomes in children with suspected beta-lactam allergy [0.03%]
疑似β内酰胺类过敏儿童的诊断方法和临床结局评估
Wang Chin Eileen Ng,Marcus Wing Choy Loe,John Zhong Heng Low et al.
Wang Chin Eileen Ng et al.
Background: Beta-lactams (BLs) are commonly implicated in hypersensitivity reactions among children. However, majority of self-reported BL allergies may be viral exanthems and antibiotics side effects. International guide...
Drug persistence of omalizumab, cyclosporine, and hydroxychloroquine in antihistamine-refractory chronic spontaneous urticaria: A biomarker-stratified real-world study [0.03%]
抗组胺药难治性慢性自发性荨麻疹患者使用奥马珠单抗、环孢素和羟氯喹的药物持久性：一项生物标志物分层的真实世界研究
Heh-Shiang Sheu,Heh-Shiang Sheu,Jun-Peng Sheu et al.
Heh-Shiang Sheu et al.
Background: Real-world comparative data on alternatives to omalizumab for antihistamine-refractory chronic spontaneous urticaria (CSU) are limited, particularly in resource-constrained Asia-Pacific settings. ...
Immunopathophysiology, biochemistry, and clinical implications of Daboia siamensis venom: A possible challenge to macrophages' immunomodulation [0.03%]
白纹腹蛇毒的免疫病理生理、生化及临床意义：对巨噬细胞免疫调节的潜在挑战
Wichit Thaveekarn,Jureeporn Noiphrom,Orawan Khow et al.
Wichit Thaveekarn et al.
Daboia siamensis (Eastern Russell's viper) envenomation remains a major public health problem in Southeast Asia and is frequently associated with severe systemic complications, particularly coagulopathy and acute kidney injury (AKI). A comp...
Hypersensitivity reactions associated with nutraceuticals and dietary supplements: A narrative review [0.03%]
保健品和膳食补充剂相关超敏反应的文献综述
Witchaya Srisuwatchari,Phawit Norchai
Witchaya Srisuwatchari
The global use of nutraceuticals and dietary supplements-including vitamins, minerals, probiotics, and botanical extracts-has increased substantially, driven largely by consumer perceptions of safety and health benefits. However, their pote...
Molecular insights and emerging therapies in shrimp & fish allergy: Contrasting perspectives from Asia and the West [0.03%]
甲壳类和鱼类过敏的分子机制及新兴疗法——来自亚洲与西方的不同观点
Agnes Sze-Yin Leung,Supaluk Tangvalelerd,Surapon Piboonpocanun et al.
Agnes Sze-Yin Leung et al.
Seafood allergy is a global health concern with substantial geographic variation in prevalence. This review examines molecular diagnostics and emerging therapies for shrimp and fish allergies, highlighting contrasting perspectives between A...
Superior magnitude and durability of hybrid immunity following SARS-CoV-2 infection [0.03%]
感染SARS-CoV-2后的杂交免疫的效果更佳且持续时间更长
Paskorn Sritipsukho,Sira Nanthapisal,Boonchu Sirichongkolthong et al.
Paskorn Sritipsukho et al.
Background: The emergence of the SARS-CoV-2 Delta variant necessitated examining hybrid immunity (vaccination- plus-infection) to optimize boosting strategies. We analyzed the kinetics, magnitude, and durability of anti-s...
External validation of the PEN-FAST clinical decision rule in children with reported penicillin allergy: A pediatric cohort study [0.03%]
儿童青霉素过敏报告的外部验证：儿科队列研究
Araya Yuenyongviwat,Kanyanee Wedchakama,Pasuree Sangsupawanich et al.
Araya Yuenyongviwat et al.
Background: Although penicillin allergy is frequently reported, the majority of labeled patients do not have confirmed hypersensitivity upon formal evaluation. The PEN-FAST clinical decision rule was developed to identify...
Allergic contact dermatitis from a clonidine transdermal patch used to treat tic disorders: First pediatric case report and literature review [0.03%]
氯代丁ин透皮贴剂治疗抽动障碍引起的接触性过敏性皮炎：首例儿科病例报告和文献回顾
Yingyang Xu,Yi Lu,Kai Guan
Yingyang Xu
Background: Recently, clonidine has been increasingly utilized for the treatment of tic disorders in children rather than for hypertension in adults. The transdermal patch is a common route of administration. Allergic con...