Planning Strategies in the Energy Sector: Integrating Bayesian Neural Networks and Uncertainty Quantification in Scenario Analysis & Optimization [0.03%]
能源部门的规划策略：在情景分析和优化中整合贝叶斯神经网络和不确定性量化
Funda Iseri,Halil Iseri,Harsh Shah et al.
Funda Iseri et al.
The global energy market faces significant challenges due to increasing demand, growing competition, and the ongoing shift toward renewable sources. Addressing these complexities requires advanced methodologies that can effectively navigate...
Caffeine, riboflavin and curcumin amended clays for PFAS binding [0.03%]
含咖啡因、核黄素和姜黄素的粘土对PFAS的吸附性能研究
Xenophon Xenophontos,Johnson O Oladele,Meichen Wang et al.
Xenophon Xenophontos et al.
Per- and polyfluoroalkyl substances (PFAS) are usually found in mixtures with other toxic compounds. Therefore, the study and design of broad acting sorbents, such as clays, is an attractive sorption solution. We previously demonstrated tha...
Systematic design of pulse dosing to eradicate persister bacteria: The case of fluoroquinolones [0.03%]
脉冲给药系统设计以消灭休眠细菌：氟喹诺酮类抗生素的案例分析
Garima Singh,Sayed Golam Mohiuddin,Sreyashi Ghosh et al.
Garima Singh et al.
A small fraction of infectious bacteria use persistence as a strategy to survive exposure to antibiotics. Pulse dosing of antibiotics, if designed well, has long been considered a potentially effective strategy towards eradication of such b...
Machine learning enabled multiscale model for nanoparticle margination and physiology based pharmacokinetics [0.03%]
基于机器学习的纳米粒子贴壁及生理基元药动学多尺度模型
Sahil Kulkarni,Benjamin Lin,Ravi Radhakrishnan
Sahil Kulkarni
This study presents a multiscale modeling framework for simulating and predicting the behavior and biodistribution of nanoparticles (NPs), focusing on applications such as targeted drug delivery. The framework encompasses two coupled models...
A hybrid statistical and machine learning based forecasting framework for the energy sector [0.03%]
一种用于能源行业的基于统计和机器学习的混合预测框架
Stefanos Baratsas,Funda Iseri,Efstratios N Pistikopoulos
Stefanos Baratsas
Energy prices are sensitive and volatile due to supply-demand imbalances, policy changes, new environmental targets, and technological breakthroughs. Energy security, sustainability, and affordability are key to policy design and societal a...
Rapid Design of Combination Antimicrobial Therapy against Acinetobacter baumannii [0.03%]
针对鲍曼不动杆菌的抗微生物联合治疗的快速设计方法
Brianna M Eales,James Smith,Nazanin Pouya et al.
Brianna M Eales et al.
Treatment of serious bacterial infections with antimicrobial agents, such as antibiotics, is a major clinical challenge, because of growing bacterial resistance to multiple agents. Combination therapy (i.e. combined dosing of more than one ...
A graph-based modeling framework for tracing hydrological pollutant transport in surface waters [0.03%]
基于图的建模框架在地表水追踪水文污染物传输的过程
David L Cole,Gerardo J Ruiz-Mercado,Victor M Zavala
David L Cole
Anthropogenic pollution of hydrological systems affects diverse communities and ecosystems around the world. Data analytics and modeling tools play a key role in fighting this challenge, as they can help identify key sources as well as trac...
PharmaPy: An object-oriented tool for the development of hybrid pharmaceutical flowsheets [0.03%]
PharmaPy：用于开发混合制药流程图的面向对象工具
Daniel Casas-Orozco,Daniel Laky,Vivian Wang et al.
Daniel Casas-Orozco et al.
Process design and optimization continue to provide computational challenges as the chemical engineering and process optimization communities seek to address more complex and larger scale applications. Software tools for digital design and ...
A benchmark simulator for quality-by-design and quality-by-control studies in continuous pharmaceutical manufacturing - Intensified filtration-drying of crystallization slurries [0.03%]
连续制药生产中质量源于设计和控制的基准模拟器-结晶浆液强化过滤干燥
Francesco Destro,Zoltan K Nagy,Massimiliano Barolo
Francesco Destro
This article introduces ContCarSim, a benchmark simulator for the development and testing of quality-by-design and quality-by-control strategies in the continuous intensified filtration-drying of paracetamol/ethanol slurries on a novel caro...
Computational fluid dynamics modeling of aerosol particle transport through lung airway mucosa [0.03%]
气溶胶颗粒通过肺部气道粘膜的计算流体动力学模型仿真研究
Blake A Bartlett,Yu Feng,Catherine A Fromen et al.
Blake A Bartlett et al.
Delivery of aerosols to the lung can treat various lung diseases. However, the conducting airways are coated by a protective mucus layer with complex properties that make this form of delivery difficult. Mucus is a non-Newtonian fluid and i...