Synthesis, Biological Evaluation and Ligand Based Pharmacophore Modeling of New Aromatic Thiosemicarbazones as Potential Anticancer Agents [0.03%]
新型芳香噻二唑卡滨类化合物的合成、生物评价及配体基于药效团建模作为潜在抗肿瘤剂研究
A Karaküçük-İyidoğan,B Aydınöz,T Taşkın-Tok et al.
A Karaküçük-İyidoğan et al.
Two series of new aromatic thiosemicarbazone derivatives were synthesized by condensation of N-(4-cyanophenyl)hydrazine carbothioamide (I) and N-(4-methylsulfanylphenyl)hydrazine carbothioamide (II) with appropriate aromatic aldehydes in or...
Toxic and Immunomodulatory Properties of an Iron(II) Coordination Complex of Isoleucyltryptophan Dipeptide [0.03%]
一种色氨酸异亮氨酰二肽配位化合物的铁（Ⅱ）配合物的毒性及免疫调节性能研究
B M Kholnazarov,N D Bunyatyan,Yu V Olefir et al.
B M Kholnazarov et al.
Results from toxicological and pharmacological studies of the iron(II) coordination complex of the immunoactive dipeptide isoleucyltryptophan (timofer) were presented. It was established that timofer was practically nontoxic and exhibited h...
Chemical Composition, Antioxidant and Antimicrobial Activities of Sanguisorba officinalis L. Extracts [0.03%]
牛舌草的化学成分、抗氧化及抗菌活性研究
Anna Gawron-Gzella,Ewa Witkowska-Banaszczak,Wiesława Bylka et al.
Anna Gawron-Gzella et al.
Sanquisorba officinalis has been used internally for the treatment of intestinal infections and duodenal ulcers, as well as hemorrhoids, phlebitis and varicose veins and female disorders, and topically to heal wounds, burns, and ulcers. In ...
Synthesis and Anti-HIV-1 Activity of Olean-9(11),12(13)-Dien-30-Oic Acid 3β-(2-O-β-D-Glucuronopyranosyl-β-D-Glucuronopyranoside) [0.03%]
olean-9(11),12(13)-二烯-30-酸3β-(2-o-β-d-葡萄吡喃糖苷)-β-d-葡萄吡喃糖苷的合成及其抗艾滋病病毒活性研究
L A Baltina Jr,O V Stolyarova,R M Kondratenko et al.
L A Baltina Jr et al.
The glycyrrhizic acid (GA) analog olean-9(11),12(13)-dien-30-oic acid 3β-(2-O-β-D-glucuronopyranosyl-β-D-glucuronopyranoside) (II) was synthesized via reduction of GA by NaBH4 in refluxing 2-PrOH:H2O with subsequent work up with HCl (5%)...
Synthesis and antiviral activity of 18α-glycyrrhizic acid and its esters [0.03%]
18α-甘草酸及其酯的合成与抗病毒活性研究
L A Baltina Jr,O V Stolyarova,L A Baltina et al.
L A Baltina Jr et al.
New esters (sulfate, nicotinates, and 4-methoxycinnamate) of 18α-glycyrrhizic acid (18α-GA) were synthesized; these were D/E-trans-isomers of natural 18β-GA (GA), which is the major triterpene glycoside in the roots of Spanish licorice a...
S A Kedik,E I Yartsev,I E Stanishevskaya
S A Kedik
The biological (antiviral) activity of a dried purified extract of Stevia was evaluated in vitro. Tests were performed using Teschen disease virus, infectious rhinotracheitis virus, and human coronavirus. ...
Synthesis and biological activity of water-soluble polymer complexes of arbidol [0.03%]
阿比多尔水溶性聚合物复合物的合成及其生物活性研究
M Yu Eropkin,M V Solovskii,M Yu Smirnova et al.
M Yu Eropkin et al.
We have synthesized water-soluble complexes between the antiviral drug arbidol and polymer compounds with molecular masses of 19-31 kDa representing copolymers of acrylamide (AA) and 2-acrylamido-2-methylpropanesulfonic acid (AAMPS). The co...
Prospects for the creation of new antiviral drugs based on glycyrrhizic acid and its derivatives (a review) [0.03%]
甘草酸及其衍生物抗病毒药物研究进展(综述)
L A Baltina,R M Kondratenko,L A Baltina Jr et al.
L A Baltina et al.
The review is devoted to the problem of creating new antiviral drugs based on glycyrrhizic acid (GA), the major triterpene glycoside extracted from roots of common and Ural licorice (Glycyrrhiza glabra L. and G. uralensis Fisher, respective...
Synthesis and antiviral activity of hydroxyalkyl-2-benzyl-and 2-[α-hydroxy-benzyl]benzimidazoles [0.03%]
羟基烷基-2-苯甲基和2-[α-羟基苯甲基]苯并咪唑的合成及其抗病毒活性研究
A É Yavorskii,L N Reshot&#x;ko,A A Kucheryavenko et al.
A É Yavorskii et al.
EFFECT OF NEW PYRIDOXAL PHOSPHATE ARYLAZO DERIVATIVES ON THE ECTO-ATPase ACTIVITY IN GUINEA PIG TISSUES [0.03%]
新的维生素B6衍生物对 Guinea pig 器官膜外 ATP 酶活性的影响
A U Ziganshin,A P Zaitsev,I P Zaitseva et al.
A U Ziganshin et al.