Madhuca indica: A Review on the Phytochemical and Pharmacological Aspects [0.03%]
Madhuca indica：药用植物化学和药理学方面研究进展综述
Priyanka Roat,Sonal Hada,Bhawna Chechani et al.
Priyanka Roat et al.
Madhuca indica J.F. Gmel. (family: Sapotaceae), commonly known as Mahua in Indian dialects, occupies the importance as one of the fuel-efficient, energy-saving plant species. Extensive studies showed that the presence of phytochemicals e.g....
Synthesis, Characterization, and Antibacterial Activity of New Isatin Derivatives [0.03%]
新型吲哚芳乙酸衍生物的合成、表征及抗菌活性研究
Sumitra Nain,Garima Mathur,Tulika Anthwal et al.
Sumitra Nain et al.
1H-indol-2,3-dione (isatin) class of biologically active compounds have analgesic, anti-microbial, anti-inflammatory, anti-tubercular, anti-proliferative properties, and is also useful for the treatment of SARS-CoV. Schiff bases containing ...
Strategy for the Choice of Disinfectants in Practical Medicine and Production [0.03%]
实用医学和生产中消毒剂的选择策略
O Yu Bogdanova,T F Chemykh
O Yu Bogdanova
The problem of the strategy for choosing disinfectants in practical medicine is considered. The pandemic of the new coronavirus infection posed new problems for disinfectology. The expanded spectrum of disinfectants and antiseptics offered ...
A P Lakeev,N Yu Abdrashitova,O S Bryushinina et al.
A P Lakeev et al.
A procedure for the determination of oseltamivir in human plasma by high-performance liquid chromatography( tandem mass spectrometry (HPLC-MS/MS) was proposed and validated. Arapid and easy-to-use method of liquid(liquid extraction with eth...
Evaluation of Cellular Toxicity and Preclinical Safety of Using an Inhalable Liposomal form of Dexamethasone [0.03%]
评估使用吸入式脂质体形式的氢化可的松的细胞毒性和临床前安全性
O A Kulikov,D V Yunina,V P Ageev et al.
O A Kulikov et al.
A liposomal form of dexamethasone was obtained. Liposomal vesicles were formed. The efficiency of incorporating dexamethasone into the liposomes was 99.7%. The cytotoxicity of the obtained liposomes was studied on a culture of human lung fi...
New Analytical Methods for the Determination of New Anti-Viral Drug Favipiravir: A Potential Therapeutic Drug Against Covid-19 Virus, in Bulk and Dosage Forms [0.03%]
新抗病毒药物法维拉韦的新型分析方法：批量和剂量形式中的一种潜在治疗药物针对Covid-19病毒
Nandeesha Itigimatha,Kailash S Chadchan,Basappa C Yallur et al.
Nandeesha Itigimatha et al.
Simple, accurate and robust analytical methods have been developed and validated for the determination of favipiravir (FVPR) by RP-HPLC and UV spectroscopy techniques as per the ICH guidelines. In the RP-HPLC method for FVPR determination, ...
A L Berkovskii,E V Sergeeva,M G Chernobrovkin et al.
A L Berkovskii et al.
The optimal conditions for analysis of low-molecular-weight heparin (LMWH) drugs by the Heptest and the metrological characteristics of the Heptest method were determined. The effects of two LMWH preparations of enoxaparin sodium, the domes...
Pharmacological Strategies for Overcoming Multidrug Resistance to Chemotherapy [0.03%]
克服化疗多药耐药性的药理学策略
T A Fedotcheva,N L Shimanovsky
T A Fedotcheva
Actual mechanisms of multidrug resistance (MDR) to chemotherapy in oncology are considered. ABC-transporters such as P-glycoprotein, BCRP protein, and MRP proteins take part in the development of resistance. The review presents the main cla...
Ethionamide and Prothionamide Based Coumarinyl-Thiazole Derivatives: Synthesis, Antitubercular Activity, Toxicity Investigations and Molecular Docking Studies [0.03%]
基于埃托那米德和普罗硫胺的香豆素噻唑衍生物：合成、抗结核活性、毒性研究及分子对接研究
Mohd Imran
Mohd Imran
The goal of this research work was to prepare and evaluate the antitubercular (anti-TB) activity of ethionamide (ETH) and prothionamide (PTH) based coumarinyl-thiazole derivatives. ETH and PTH were reacted with coumarin intermediates (3a-3e...
Nutan Rao,Tushar Poojari,Charvi Poojary et al.
Nutan Rao et al.
Drug repurposing has proved to be an efficient alternative to drug discovery owing to the facts that it is economical and risk factors being much lower or even negligible as the drug has already been approved for having safe use in humans. ...