V V Yagov,I V Yagova
V V Yagov
Cathodic electrochemiluminescence (CECL) of hydroxychloroquine (HCQ) in aqueous solutions on an aluminum electrode is described. The analytical possibilities of the phenomenon are evaluated. The conditions for HCQ determination in slightly ...
The Effect of Phytocompounds of Medicinal Plants on Coronavirus (2019-NCOV) Infection [0.03%]
植物药用化合物对新型冠状病毒（2019-nCoV）感染的影响
Ahlem Zrig
Ahlem Zrig
The recent outbreak of coronavirus disease 2019 (COVID-19) is a respiratory infection and it can spread from animal to person, person to person through coughing or physical contact. Recent studies revealed that the genome sequence of this p...
Potential for the Development of a New Generation of Aminoglycoside Antibiotics [0.03%]
新一代氨基糖苷抗生素的研发潜力
A N Tevyashova,K S Shapovalova
A N Tevyashova
The present review summarizes recent publications devoted to aminoglycosides that study the main types of resistance to antibiotics of this class and the main directions of chemical modification aimed at overcoming the resistance or changin...
On the Possibility of Reducing the Sample Size for Microbiological Examination of Some Pharmaceutical Substances [0.03%]
关于减少某些药品微生物检查的样本量的可能性探讨
M V Roshchina,O V Gunar,I A Builova
M V Roshchina
The possibility of reducing the sample size for microbiological examination of some pharmaceutical substances is considered. Trypticase-soy agar was evaluated for the ability to detect yeast and mold fungi and to isolate the minimal amount ...
A I Kalashnikov,E G Sonina,D A Kulagina et al.
A I Kalashnikov et al.
A synthetic method for the promising new drug oseltamivir ethoxysuccinate is described in detail. Various conditions for obtaining the target substance are considered. Its complete physicochemical characteristics are given. The obtained age...
Structure-Based Virtual Screening and Molecular Dynamics Simulation to Identify Potential SARS-CoV-2 Spike Receptor Inhibitors from Natural Compound Database [0.03%]
基于结构的虚拟筛选及分子动力学模拟从天然产物数据库中发现SARS-CoV-2刺突蛋白受体抑制剂潜在候选化合物
Arkadeep Sarkar,Debanjan Sen,Ashutosh Sharma et al.
Arkadeep Sarkar et al.
The outbreak of respiratory disease, COVID-19 caused by SARS-CoV-2 has now been spread globally and the number of new infections is rising every moment. There are no specific medications that are currently available to combat the disease. T...
Synthesis and Antiplatelet and Anticoagulant Activity of Thietane-Containing 2-(5-Bromo-2,4-Dihydro-3-Oxo-1,2,4-Triazolyl-4)Acetate Salts [0.03%]
含噻烷的2-(5-溴-2,4-二氢-3-氧代-1,2,4-三唑基-4)乙酸盐的合成及其抗血小板和抗凝活性研究
K G Gurevich,A L Urakov,G A Rozit et al.
K G Gurevich et al.
Sulfone II was synthesized via oxidation of ethyl 2-[5-bromo-2,4-dihydro-3-oxo-2-(thietanyl-3)-1,2,4-triazolyl- 4]acetate (I) by H2O2. Hydrolysis of esters I and II synthesized 2-[5-bromo-2,4-dihydro- 3-oxo-2-(thietanyl-3)-1,2,4-triazolyl-4...
Synthesis of Glycyrrhizic Acid Conjugates with S-Benzyl-L-Cysteine and Their Antiviral Activity [0.03%]
甘草酸与S-苄基半胱氨酸偶联衍生物的合成及抗病毒活性研究
L A Baltina,R M Kondratenko,L A Baltina Jr et al.
L A Baltina et al.
A new method for the synthesis of glycyrrhizic acid (GA) conjugates with S-benzyl-L-cysteine using 1-ethyl-3-(3-dimethylaminoproopyl)carbodiimide is proposed. It is established that 3-O-{2-O-[N-(β-D-glucopyranosyluronyl)-L-cysteine-S-benzy...
P I Savosina,D S Druzhilovskii,V V Poroikov
P I Savosina
An outbreak of a new coronavirus disease (COVID-19) in China in December 2019 became the epicenter for the spread of a global pandemic. The SARS-CoV-2 coronavirus causes a cascade of respiratory diseases similar to severe acute respiratory ...
Current Strategies in Development of New Chromone Derivatives with Diversified Pharmacological Activities: A Review [0.03%]
具有多种药理作用的新香豆素衍生物开发的最新策略：综述
Noor Ul Amin Mohsin,Muhammad Irfan,Shams Ul Hassan et al.
Noor Ul Amin Mohsin et al.
Chromone derivatives possess a spectrum of biological activities. Chromone has been recognized as a privileged structure for new drug invention and development. Substitution pattern of chromone scaffold determines different type of biologic...