Synthesis and Anti-Inflammatory Activity Evaluation of Some Benzimidazole Derivatives [0.03%]
苯并咪唑衍生物的合成及其抗炎活性评价
Alok Kumar Moharana,Rudra Narayan Dash,Nimai Charan Mahanandia et al.
Alok Kumar Moharana et al.
Hyper-inflammation aggravates the symptoms of both communicable and non-communicable diseases. Therefore, anti-inflammatory compounds may have wide therapeutic application. Benzimidazole is a privileged scaffold and its success in drug deve...
Glycoalkaloids of Plants in the Family Solanaceae (Nightshade) as Potential Drugs [0.03%]
夜shade科植物糖生物碱作为潜在药物的可能性
T O Ostreikova,O V Kalinkina,N G Bogomolov et al.
T O Ostreikova et al.
Worldwide interest in medicinal plants and related drugs is growing because of the increased spectrum of new synthetic drugs. In this context, secondary plant metabolites are most significant. This review analyzes data on the structures and...
Synthesis of Glycyrrhizic Acid Conjugates with Amino-Acid Methyl Esters and their Ability to Stimulate Antibody Genesis in Mice [0.03%]
甘草酸与氨基酸甲酯连接子的合成及其刺激小鼠产生抗体的能力研究
L A Baltina,L A Baltina Jr,S F Petrova et al.
L A Baltina et al.
Conjugates of glycyrrhizic acid (GA) with methyl esters of L-amino acids (valine, methionine, and glutamic acid) containing the amino-acid residues in the carbohydrate moiety of the glycoside were synthesized using 1-ethyl-3-(3-dimethylamin...
Assessment of the Quality of Herbal Teas from Šabac, Serbia in Terms of the Content of Heavy Metals [0.03%]
塞尔维亚Šabac市草本茶重金属含量评估
Kosana Popović,Mirjana Antonijević Nikolić,Branka Dražić et al.
Kosana Popović et al.
Chemical components of teas have received great interest because they are related to health. In this work, data on the determination of foreign matter, loss on drying/water content, total ash and ash insoluble in hydrochloric acid are prese...
Development of a Quantitative Determination Method for Aluminum Ions in Adsorbed Drugs Using Atomic Absorption Spectrometry with Electrothermal Atomization [0.03%]
采用原子吸收光谱-低温灰化法测定吸附药物中铝离子的含量研究
D D Makarishcheva,O N Kolesnikova,V E Tregubova et al.
D D Makarishcheva et al.
A quantitative determination method for Al3+ in immunobiological drugs using atomic absorption spectroscopy with electrothermal atomization was developed. Conditions for the preparation of aluminum hydroxide gel were selected [NaOH (5 M), h...
Viral Safety Issues in the Production and Manufacturing of Human Immunoglobulin Preparations from Equine Plasma/Serum [0.03%]
源于马血浆/血清的人免疫球蛋白制品的生产与制造中的病毒安全问题
V V Mashin,A N Sergeev,N N Martynova et al.
V V Mashin et al.
The current Russian and foreign pharmacopoeias either do not provide any information about existing types of viral diseases in horses or do not present it in full. Data of modern domestic and foreign literature was used to prepare the most ...
V V Mashin,A N Sergeev,N N Martynova et al.
V V Mashin et al.
Equine blood plasma/serum and intermediates must be monitored for the presence of live viruses pathogenic in humans during production of equine immunoglobulins. Information concerning low-cost and simple methods for the detection of live ho...
Physicochemical Properties and Methods of Analysis of Vildagliptin (Review) [0.03%]
维格列汀的理化性质及分析方法研究(文献复习)
E B Polyakova,D R Sabirzyanov,N A Prozorova et al.
E B Polyakova et al.
Vildagliptin is an oral agent which is a member of a new class of hypoglycemic drugs, dipeptidylpeptidase-4 (DPP-4) inhibitors. This review presents the physicochemical properties of vildagliptin and assesses analysis methods for its estima...
S V Orlova,V V Tatarinov,E A Nikitina et al.
S V Orlova et al.
Dihydroquercetin (DHQ) is a bioflavonoid with high antioxidant, capillary-protective, and anti-inflammatory activity. DHQ has previously been used for treating Middle East respiratory syndrome coronavirus (MERS-CoV) infection and is current...
Prospects of a Transdermal Dosage Form (Microneedles) and Justification of the Active Substance Selection for Development of a New Medicine [0.03%]
经皮给药系统(微针)的发展前景及新药研发的活性物质选择依据
U V Nogaeva,A A Leshkevich,D S Yurochkin et al.
U V Nogaeva et al.
Prospects for the development of a transdermal dosage form (DF) based on microneedles were considered. Methods for obtaining such systems, the application areas, and data from the pharmaceutical market were examined. A wide sample of INNs t...