Philippe Lefebvre,Perrine J Martin,Sébastien Flajollet et al.
Philippe Lefebvre et al.
Vitamin A derivatives plays a crucial role in embryonic development, as demonstrated by the teratogenic effect of either an excess or a deficiency in vitamin A. Retinoid effects extend however beyond embryonic development, and tissue homeos...
Daniel Lechner,Enikö Kállay,Heide S Cross
Daniel Lechner
Because colorectal cancer (CRC) is a leading cause of cancer mortality in the Western industrialized world, future chemopreventive strategies will be of high socioeconomic importance. Lower CRC incidences in Far Eastern countries in part ma...
Thyroid hormone transporters [0.03%]
甲状腺激素转运体
Edith C H Friesema,Jurgen Jansen,Carmelina Milici et al.
Edith C H Friesema et al.
Thyroid hormone is essential for the development of the brain and the nervous system. Cellular entry is required for conversion of thyroid hormones by the intracellular deiodinases and for binding of T(3) to its nuclear receptors. Several t...
Mary E Gerritsen,Graham F Wagner
Mary E Gerritsen
Stanniocalcin was originally described as a hormone with calcitonin-like actions in fish. During the last decade, mammalian forms of stanniocalcin have been identified, and this discovery has led to important advances in our understanding o...
Amy W Rachfal,David R Brigstock
Amy W Rachfal
The CCN family currently comprises six members (CCN1-6) that regulate diverse cell functions, including mitogenesis, adhesion, apoptosis, extracellular matrix (ECM) production, growth arrest, and migration. These properties can result in a ...
I Andrade Ferreira,J W N Akkerman
I Andrade Ferreira
The expected explosive increase in the number of patients with diabetes mellitus will increase the stress on health care. Treatment is focused on preventing vascular complications associated with the disorder. In order to develop better tre...
Hippokratis Kiaris,Andrew V Schally,Anastasios Kalofoutis
Hippokratis Kiaris
Growth hormone-releasing hormone (GHRH) is a neuropeptide secreted by the hypothalamus that stimulates the synthesis and release of growth hormone (GH) in the pituitary. Accumulating evidence suggests that in addition to GHRH's neuroendocri...
Role of magnesium, coenzyme Q10, riboflavin, and vitamin B12 in migraine prophylaxis [0.03%]
镁、辅酶Q10、核黄素和维生素B12在偏头痛预防中的作用
Alfredo Bianchi,Salvatore Salomone,Filippo Caraci et al.
Alfredo Bianchi et al.
Migraine is a neurovascular syndrome characterized by recurrent headache associated with other symptoms, eventually preceded by aura. This chapter reviews the involvement of some mineral, coenzyme, and vitamin defects in the pathogenesis of...
Plasma retinol-binding protein: structure and interactions with retinol, retinoids, and transthyretin [0.03%]
血浆视黄醇结合蛋白：结构及其与视黄醇、维甲酸和甲状腺转运蛋白的相互作用
Giuseppe Zanotti,Rodolfo Berni
Giuseppe Zanotti
Retinol-binding protein (RBP) is the retinol-specific transport protein present in plasma. The available crystal structures of different forms of RBP have provided details of the interactions of this binding protein with retinol, retinoids,...
Regulation of expression of the Na+/H+ exchanger by thyroid hormone [0.03%]
甲状腺素对Na+/H+交换器表达的调节作用研究进展
Emily Slepkov,Larry Fliegel
Emily Slepkov
The Na+/H+ exchanger is a pH regulatory protein with a ubiquitous distribution in eukaryotic cells. Several isoforms of the Na+/H+ exchanger are known. The first isoform to be characterized and cloned, NHE1, is present on the plasma membran...