Bilateral macronodular and micronodular hyperplasia: Biochemical, radiological and genetic diagnosis [0.03%]
双侧大节结和微节结样增生的生化、影像及基因诊断
Víctor Navas-Moreno,Carolina Sager-La Ganga,María Sara Tapia-Sanchiz et al.
Víctor Navas-Moreno et al.
Adrenal-origin Cushing's syndrome (CS) accounts for up to 30 percent of cases, with approximately 10 percent attributable to bilateral adrenal disease. The fifth edition of the WHO classification has redefined the terminology previously ref...
Andrés E Ortiz-Flores
Andrés E Ortiz-Flores
Cushing´s syndrome (CS) is a heterogeneous disorder characterized by chronic exposure to cortisol excess, leading to significant metabolic and cardiovascular complications. Timely diagnosis is crucial to reduce morbidity and mortality in t...
Queralt Asla,Eulàlia Urgell,Sílvia Terzan et al.
Queralt Asla et al.
Hypercortisolism constitutes several symptoms and signs due to inappropriately high and prolonged exposure to excess glucocorticoids (GCs), known as Cushing's syndrome (CS). While iatrogenic corticosteroid administration is the most frequen...
Qiang Zhao,Oana C Sima,Mariona Estape et al.
Qiang Zhao et al.
Diagnosing endogenous autonomous hypercortisolism, spanning from autonomous cortisol secretion to overt Cushing syndrome, remains challenging because of the heterogeneous clinical presentation and the variability of cortisol secretion patte...
Laura González Fernández,Rogelio García Centeno
Laura González Fernández
Endogenous Cushing's syndrome (CS) is characterized by chronic glucocorticoid excess that drives a severe cardiometabolic phenotype responsible for most morbidity and mortality associated with the disorder. Cortisol excess induces a constel...
Clara González-Pérez,Sergio Pedraza-Arevalo,Justo P Castaño et al.
Clara González-Pérez et al.
Cushing's syndrome comprises a heterogeneous group of disorders characterized by chronic excess of glucocorticoid release from adrenal glands, caused by altered adrenal function or by ACTH hypersecretion from pituitary or ectopic sources. A...
Betina Biagetti
Betina Biagetti
Cushing's syndrome (CS) during pregnancy is an exceptionally rare but high-risk condition that poses major diagnostic and therapeutic challenges. Its low prevalence is mainly due to cortisol-induced infertility. Although its low prevalence ...
Leonor Pinto,Sara Donato
Leonor Pinto
Mild autonomous cortisol secretion (MACS) is the most frequent hormonal alteration identified in patients with adrenal incidentalomas and is characterized by adrenocorticotropic hormone (ACTH)-independent cortisol hypersecretion in the abse...
Cyclic Cushing's syndrome [0.03%]
周期性库欣综合征
Elisabeth Nowak
Elisabeth Nowak
While physiological cortisol secretion follows a regulated circadian rhythm, pathological excess as in endogenous Cushing's syndrome is characterised by increased and dysregulated cortisol concentrations. While subtle fluctuations occur in ...
Valentina Morelli,Antonio Musolino
Valentina Morelli
ectopic Cushing syndrome (ECS) is a rare endocrinological disease caused by neuroendocrine tumors capable of secreting ATCH or POMC derived immature peptides. It accounts for 10-20 percent of Cushing syndrome cases. ACTH secretion usually l...