Control of interleukin-2 gene transcription: a paradigm for inducible, tissue-specific gene expression [0.03%]
控制白细胞介素-2基因转录:诱导型和组织特异性基因表达的典范
Karen Bunting,Jun Wang,M Frances Shannon
Karen Bunting
Interleukin-2 (IL-2) is a key cytokine that controls immune cell function, in particular the adaptive arm of the immune system, through its ability to control the clonal expansion and homeostasis of peripheral T cells. IL-2 is produced almo...
Ronaldo Alves Pinto Nagem,José Ribamar Ferreira Júnior,Laure Dumoutier et al.
Ronaldo Alves Pinto Nagem et al.
Interleukin-22 (IL-22) is a cytokine that regulates the production of acute phase proteins of the immunological response. On binding to its cognate receptor (IL-22R1), which is associated to the interleukin-10 receptor 2 (IL-10R2), IL-22 pr...
Alexander Zdanov
Alexander Zdanov
The interleukin-19 (IL-19) subfamily of cytokines is part of a larger family of homologs of IL-10 that includes two groups of proteins: five viral cytokines, and eight cellular cytokines, having quite different biological activities. Among ...
Crystal structures and inhibitors of proteins involved in IL-2 release and T cell signaling [0.03%]
与IL-2释放和T细胞信号传导相关蛋白质的晶体结构和抑制剂
Kieron Brown,Graham M T Cheetham
Kieron Brown
IL-3, IL-5, and GM-CSF signaling: crystal structure of the human beta-common receptor [0.03%]
人β共用链信号转导蛋白的晶体结构(IL-3、IL-5和GM-CSF)
James M Murphy,Ian G Young
James M Murphy
The cytokines, interleukin-3 (IL-3), interleukin-5 (IL-5), and granulocyte-macrophage colony stimulating factor (GM-CSF), are polypeptide growth factors that exhibit overlapping activities in the regulation of hematopoietic cells. They appe...
J Grassmann
J Grassmann
Plant antioxidants are composed of a broad variety of different substances like ascorbic acid and tocopherols, polyphenolic compounds, or terpenoids. They perform several important functions in plants and humans (e.g., carotenoids function ...
Tadao Asami,Takeshi Nakano,Shozo Fujioka
Tadao Asami
In animals, a large number of steroid hormones play important roles in numerous processes including reproduction and differentiation. The biologically active plant steroid brassinolide (BL) was first discovered in the pollen of western rape...
Plant sex pheromones [0.03%]
植物性信息素
Hiroyuki Sekimoto
Hiroyuki Sekimoto
Although plant pheromones have been much less studied than animal pheromones, they are involved in a wide variety of processes in the life cycle of many plants, particularly in sexual reproduction. In this review, the current knowledge conc...
John Browse
John Browse
Jasmonic acid is an oxylipin signaling molecule derived from linolenic acid. So far, jasmonate (JA) (including the free acid and a number of conjugates) has been shown to regulate or co-regulate a wide range of processes in plants, from res...
Annelies De Paepe,Dominique Van der Straeten
Annelies De Paepe
Hormones are key regulators of plant growth and development. Genetic and biochemical studies have identified major factors that mediate ethylene biosynthesis and signal transduction. Substantial progress in the elucidation of the ethylene s...