Debbie J Mustacich,Richard S Bruno,Maret G Traber
Debbie J Mustacich
The term vitamin E is used to describe eight lipophilic, naturally occurring compounds that include four tocopherols and four tocotrienols designated as alpha-, beta-, gamma-, and delta-. The most well-known function of vitamin E is that of...
Richard C Baybutt,Agostino Molteni
Richard C Baybutt
Within the last several years, research scientists and clinicians have been intrigued with the potential use of an active form of vitamin A, retinoic acid (RA), for the treatment and prevention of emphysema. The interest in this area can be...
Saurabh Mehta,Wafaie Fawzi
Saurabh Mehta
An estimated 25 million lives have been lost to acquired immune-deficiency syndrome (AIDS) since the immunodeficiency syndrome was first described in 1981. The progress made in the field of treatment in the form of antiretroviral therapy (A...
Cytodifferentiation by retinoids, a novel therapeutic option in oncology: rational combinations with other therapeutic agents [0.03%]
维甲酸介导的细胞分化——一项新颖的抗癌策略：与其他疗法合理联用的可能性
Enrico Garattini,Maurizio Gianni&#x;,Mineko Terao
Enrico Garattini
Retinoic acid (RA) and derivatives are promising antineoplastic agents endowed with both therapeutic and chemopreventive potential. Although the treatment of acute promyelocytic leukemia with all-trans retinoic acid is an outstanding exampl...
Samarjit Das,Kalanithi Nesaretnam,Dipak K Das
Samarjit Das
Retinoic acid and the heart [0.03%]
视黄酸与心脏发育
Jing Pan,Kenneth M Baker
Jing Pan
Retinoic acid (RA), the active derivative of vitamin A, by acting through retinoid receptors, is involved in signal transduction pathways regulating embryonic development, tissue homeostasis, and cellular differentiation and proliferation. ...
Peter P Fu,Qingsu Xia,Mary D Boudreau et al.
Peter P Fu et al.
The skin is similar to other organs in how it absorbs, stores, and metabolizes vitamin A. However, because of the anatomical location of skin and the specialized physiological roles it plays, there are ways in which the skin is rather uniqu...
Vitamin A supplementation and retinoic acid treatment in the regulation of antibody responses in vivo [0.03%]
维生素A补充和视黄酸治疗对体液免疫的调节作用
A Catharine Ross
A Catharine Ross
Vitamin A (VA, retinol) is essential for normal immune system maturation, but the effect of VA(1) on antibody production, the hallmark of successful vaccination, is still not well understood. In countries where VA deficiency is a public hea...
Use of model-based compartmental analysis to study vitamin A kinetics and metabolism [0.03%]
基于模型的隔室分析在研究维生素A动力学和代谢中的应用
Christopher J Cifelli,Joanne Balmer Green,Michael H Green
Christopher J Cifelli
We discuss the use of mathematical modeling, and specifically model-based compartmental analysis, to analyze vitamin A kinetic data obtained in rat and human studies over the past 25 years. Following an overview of whole-body vitamin A meta...
Haruki Senoo,Naosuke Kojima,Mitsuru Sato
Haruki Senoo
Hepatic stellate cells (HSCs; also called as vitamin A-storing cells, lipocytes, interstitial cells, fat-storing cells, Ito cells) exist in the space between parenchymal cells and sinusoidal endothelial cells of the hepatic lobule, and stor...