Xing Gong,Ramana Gutala,Anil K Jaiswal
Xing Gong
Vitamin K1, K2, and K3 are essential nutrients associated with blood clotting and bone metabolism. Quinone oxidoreductases [NAD(P)H:quinone oxidoreductase 1 (NQO1) and NRH:quinone oxidoreductase 2 (NQO2)] are among the selected enzymes that...
Mario A Bianchet,Sabri Bora Erdemli,L Mario Amzel
Mario A Bianchet
Quinone reductases type 1 (QR1) are FAD-containing enzymes that catalyze the reduction of many quinones, including menadione (Vit K3), to hydroquinones using reducing equivalents provided by NAD(P)H. The reaction proceeds with a ping-pong m...
The vitamin K cycle [0.03%]
维生素K循环
Johannes Oldenburg,Milka Marinova,Clemens Müller-Reible et al.
Johannes Oldenburg et al.
Vitamin K is a collective term for lipid-like naphthoquinone derivatives synthesized only in eubacteria and plants and functioning as electron carriers in energy transduction pathways and as free radical scavengers maintaining intracellular...
Andrea A Garcia,Pieter H Reitsma
Andrea A Garcia
Vitamin K epoxide, a product of gamma-carboxylation, must be rapidly recycled to its reduced form before it can be reused. The set of sequential reactions that guarantees vitamin K recycling is known as the vitamin K cycle. This review is f...
Sarah L Booth,Ala Al Rajabi
Sarah L Booth
To understand the role of vitamin K in human health, it is important to identify determinants of vitamin K status throughout the life cycle. Our current understanding of vitamin K physiology and metabolism only partially explains why there ...
Vitamin K. Preface [0.03%]
维生素K 目次
Gerald Litwack
Gerald Litwack
Novel connections between the neuroendocrine and immune systems: the ghrelin immunoregulatory network [0.03%]
神经内分泌系统与免疫系统的新型联系：胃泌素免疫调节网络
Dennis D Taub
Dennis D Taub
There appears to be bidirectional communication between the neuroendocrine and immune systems. This communication is mediated by way of an array of cytokines, hormones, and neuropeptides. Inflammatory cytokines released by immune cells have...
Ghrelin and prostate cancer [0.03%]
胃饥饿素和前列腺癌
Fabio Lanfranco,Matteo Baldi,Paola Cassoni et al.
Fabio Lanfranco et al.
Ghrelin, a 28-amino acid octanoylated peptide predominantly produced by the stomach, has been discovered to be a natural ligand of the type 1a growth hormone secretagogue receptor (GHSR1a). Ghrelin has recently attracted the interest as a n...
Ghrelin and reproduction: ghrelin as novel regulator of the gonadotropic axis [0.03%]
胃泌素与生殖：胃泌素是调控下丘脑-垂体-性腺轴的新因素
Manuel Tena-Sempere
Manuel Tena-Sempere
Identification of ghrelin in late 1999, as the endogenous ligand of the growth hormone secretagogue receptor (GHSR), opened up a new era in our understanding of the regulatory mechanisms of several neuroendocrine systems, including growth a...
Jens Fuglsang
Jens Fuglsang
Ghrelin and its receptors are found in the reproductive organs and in the placenta, clearly indicating a role for ghrelin in reproduction. Circulating ghrelin levels peak at mid-gestation, then with advancing gestational age declining ghrel...