Juvenile hormone receptor Methoprene tolerant: Functions and applications [0.03%]
甲氧基苯丙酸耐受基因（Met）的的功能及其应用研究进展
Subba Reddy Palli
Subba Reddy Palli
During the past 15years, after confirming Methoprene tolerant (Met) as a juvenile hormone (JH) receptor, tremendous progress has been made in understanding the function of Met in supporting JH signal transduction. Met role in JH regulation ...
Barbara J Clark,Carolyn M Klinge
Barbara J Clark
Dehydroepiandrosterone (3β-hydroxy-5-androsten-17-one, DHEA) and its sulfated metabolite DHEA-S are the most abundant circulating steroids and are precursors for active sex steroid hormones, estradiol and testosterone. DHEA has a broad ran...
Livio Casarini,Manuela Simoni
Livio Casarini
Follicle-stimulating hormone (FSH) and estrogens are fundamental to support reproductive functions. Beside the well-known FSH membrane receptor (FSHR), a G protein-coupled estrogen receptor (GPER) has been found, over the last two decades, ...
Naoki Okamoto,Daiki Fujinaga,Naoki Yamanaka
Naoki Okamoto
Ecdysteroids are a group of steroid hormones in arthropods with pleiotropic functions throughout their life history. Ecdysteroid research in insects has made a significant contribution to our current understanding of steroid hormone signali...
Essential and subtype-dependent function of thyroid hormone receptors during Xenopus metamorphosis [0.03%]
甲状腺激素受体在非洲爪蟾变态过程中的功能作用
Yun-Bo Shi,Yuta Tanizaki,Shouhong Wang et al.
Yun-Bo Shi et al.
Thyroid hormone (T3) plays critical roles in organ metabolism and development in vertebrates. Anuran metamorphosis is perhaps the most dramatic and best studied developmental process controlled by T3. Many changes in different organs/tissue...
Steroid-receptor coactivator complexes in thyroid hormone-regulation of Xenopus metamorphosis [0.03%]
甲状腺激素调节非洲爪蟾变态反应中的类固醇受体共激活复合物的作用
Yuta Tanizaki,Lingyu Bao,Yun-Bo Shi
Yuta Tanizaki
Anuran metamorphosis is perhaps the most drastic developmental change regulated by thyroid hormone (T3) in vertebrate. It mimics the postembryonic development in mammals when many organs/tissues mature into adult forms and plasma T3 level p...
The androgen receptor [0.03%]
雄激素受体
Greg Van-Duyne,Ian A Blair,Cynthia Sprenger et al.
Greg Van-Duyne et al.
The Androgen Receptor (AR) is a ligand (androgen) activated transcription factor and a member of the nuclear receptor (NR) superfamily. It is required for male sex hormone function. AR-FL (full-length) has the domain structure of NRs, an N-...
Nicolas C Nicolaides,George P Chrousos
Nicolas C Nicolaides
Glucocorticoids are members of steroid hormones that are biosynthesized in the intermediate cellular zone of the adrenal cortex (zona fasciculata) and released into the peripheral blood as final products of the hypothalamic-pituitary-adrena...
Raj Kumar
Raj Kumar
The steroid hormone receptors (SHRs) belong to the large superfamily of nuclear receptors that selectively modulate gene expression in response to specific hormone ligands. The SHRs are required in a broad range of normal physiological proc...
Cryo-EM technique and its application: Structure of steroid hormone receptors [0.03%]
冷冻电镜技术及其应用：类固醇激素受体的结构研究
Raj Kumar
Raj Kumar
In recent years, cryo-electron microscopy (cryo-EM) has become one of the most powerful tools to solve the 3-D structure of macromolecules. Unlike X-ray crystallography, the cryo-EM method has advantage of providing an in-depth insight into...