K G Kemoklidze,N A Tyumina
K G Kemoklidze
Without knowledge of the spatial [three-dimensional, (3D)] organization of an organ at the tissue and cellular levels, it is impossible to form a complete picture of its structure and function. At the same time, tissue components hidden in ...
Andreas Yiallouris,Charalampos Filippou,Sophia C Themistocleous et al.
Andreas Yiallouris et al.
This article discusses the physiological and anatomical changes of adrenal gland with age and the effects this has overall on how the organ responds to stress. Physiological changes entail a decrease in adrenocorticoid hormone secretion how...
Yuan Kang,Karly Laprocina,Huifei Sophia Zheng et al.
Yuan Kang et al.
Mouse models have been widely used in the study of adrenal gland development and diseases. The X-zone is a unique structure of the mouse adrenal gland and lineage-tracing studies show that the X-zone is a remnant of the fetal adrenal cortex...
Adaptive remodeling of the stimulus-secretion coupling: Lessons from the 'stressed' adrenal medulla [0.03%]
刺激-分泌偶联的适应性重塑：“应激”肾上腺髓质的启示
Nathalie C Guérineau
Nathalie C Guérineau
Stress is part of our daily lives and good health in the modern world is offset by unhealthy lifestyle factors, including the deleterious consequences of stress and associated pathologies. Repeated and/or prolonged stress may disrupt the bo...
Genetic variants in the renin-angiotensin-aldosterone system: Impact on cancer risk, prognosis, and therapeutic directions [0.03%]
肾素血管紧张素醛固酮系统中的基因变异：对癌症风险，预后和治疗方向的影响
Muhammad T Abdel Ghafar,Aya A Helmy
Muhammad T Abdel Ghafar
Although renin-angiotensin-aldosterone system (RAAS) is known to maintain blood pressure and electrolyte balance, it has recently been linked to a number of biological processes such as angiogenesis, tumorigenesis, metastasis, and cellular ...
Scott M MacKenzie,Lara A Birch,Stelios Lamprou et al.
Scott M MacKenzie et al.
Aldosterone is a cardiovascular hormone with a key role in blood pressure regulation, among other processes, mediated through its targeting of the mineralocorticoid receptor in the renal tubule and selected other tissues. Its secretion from...
MicroRNA regulation of adrenal glucocorticoid and androgen biosynthesis [0.03%]
微小核糖核酸对肾上腺皮质激素和雄激素生物合成的调节作用
Salman Azhar,Wen-Jun Shen,Zhigang Hu et al.
Salman Azhar et al.
Steroid hormones are derived from a common precursor molecule, cholesterol, and regulate a wide range of physiologic function including reproduction, salt balance, maintenance of secondary sexual characteristics, response to stress, neurona...
Gerald Litwack
Gerald Litwack
Structures of the arginine-vasopressin and oxytocin receptor signaling complexes [0.03%]
精氨酸加压素和催产素受体信号复合物的结构
Julien Bous,Aurélien Fouillen,Hélène Orcel et al.
Julien Bous et al.
Arginine-vasopressin (AVP) and oxytocin (OT) are neurohypophysial hormones which share a high sequence and structure homology. These are two cyclic C-terminally amidated nonapeptides with different residues at position 3 and 8. In mammals, ...
Shristi Pawnikar,Sana Akhter,Yinglong Miao
Shristi Pawnikar
Membrane proteins such as G protein-coupled receptors (GPCRs) are involved in awide range of physiological and pathological cellular processes. Binding of extracellular signals to GPCRs, including hormones, neurotransmitters, peptides and p...