Histopathological features of aldosterone-producing lesions according to their different somatic genetic mutations [0.03%]
不同体细胞基因突变引起的醛固酮增多症病变的病理特征分析
Xin Gao,Yuto Yamazaki,Yoshikiyo Ono et al.
Xin Gao et al.
Primary aldosteronism (PA) is composed of different aldosterone-producing lesions including aldosterone-producing adenoma (APA), aldosterone-producing micronodules (APM), aldosterone-producing nodules (APN) and aldosterone-producing diffuse...
Tithi Bhattacharyya,Pritam Das,Rajkumar Banerjee
Tithi Bhattacharyya
Steroid Hormone Receptors (SHRs) when bound to its ligand can act as transcription factors, which are responsible for transcription of important genes via hormone responsive element in our genome. Many studies have revealed the molecular me...
About the editor [0.03%]
关于编辑者
Self-assembly of the insulin-responsive vesicles creates a signaling platform for the insulin action on glucose uptake [0.03%]
胰岛素响应囊泡的自我组装为葡萄糖吸收的胰岛素作用创造了信号平台
Konstantin V Kandror
Konstantin V Kandror
In fat and skeletal muscle cells, insulin causes plasma membrane translocation of specialized insulin-responsive vesicles, or IRVs. These vesicles consist of multiple copies of Glut4, sortilin, IRAP, and LRP1 as well as several auxiliary co...
The molecular mechanism underlying the human glucose facilitators inhibition [0.03%]
人葡萄糖易化剂抑制作用的分子机制
Cantao Quan,Xin Jiang
Cantao Quan
Glucose is the primary energy substrate and an essential precursor for cellular metabolism. Maintaining glucose homeostasis necessitates the presence of glucose transporters, as the hydrophilic nature of glucose prevents its passage across ...
Atrayee Chattopadhyay,Mohor Mitra,Mrinal K Maiti
Atrayee Chattopadhyay
Xylose constitutes the second major sugar fraction of the plant-derived lignocellulosic biomass, which is the most abundantly available and renewable feedstock for microbial fermentations. Hence, comprehensive utilization of xylose is cruci...
Makoto Kawatani,Hiroyuki Osada
Makoto Kawatani
Facilitative glucose transporters (GLUTs) encoded by the SLC2A genes mediate the initial steps of sugar utilization in cells. Fourteen existing GLUT family members are classified into three subclasses based on the characteristics of the gen...
Ajeesh Babu Littleflower,Sulfath Thottungal Parambil,Gisha Rose Antony et al.
Ajeesh Babu Littleflower et al.
Breast cancer is a widely prevalent and devastating morbidity that affects millions of women around the world. Conventional treatment options for breast cancer include surgery, chemotherapy, and radiotherapy. However, these therapies can fr...
L Mardones
L Mardones
Vitamin C is a crucial water-soluble antioxidant and an essential cofactor for enzymes like proline and lysine hydroxylases, playing a vital role in cellular physiology. While sodium-dependent ascorbate co-transporters (SVCT1 and SVCT2) are...
Nazim Uddin Afzal,Mir Ekbal Kabir,Hiranmoy Barman et al.
Nazim Uddin Afzal et al.
Glucose is the primary source of energy for most of the cells and essential for basic functionalities of life's biochemical processes. Transportation of glucose via biological membranes is essential for life mediated by glucose transporters...