Epigenetics, endometriosis and sex steroid receptors: An update on the epigenetic regulatory mechanisms of estrogen and progesterone receptors in patients with endometriosis [0.03%]
表观遗传学、子宫内膜异位症和性类固醇受体：雌激素和孕酮受体的表观遗传调控机制的新进展
Margherita Rossi,Isabelle Seidita,Silvia Vannuccini et al.
Margherita Rossi et al.
Endometriosis is a benign gynecological disease affecting ∼10% of reproductive-aged women and is defined as the presence of endometrial glands and stroma outside the uterine cavity. Endometriosis can cause a variety of health problems, fro...
Suneesh Kaimala,Suraiya Anjum Ansari,Bright Starling Emerald
Suneesh Kaimala
Type 2 diabetes (T2D) is a metabolic disease characterized by the development of β-cell dysfunction with hepatic, muscular and adipose tissue insulin resistance. Although the molecular mechanisms leading to its development are not entirely...
The potential role of environmental factors in modulating mitochondrial DNA epigenetic marks [0.03%]
环境因素在调节线粒体DNA表观遗传学特征中潜在作用的可能性研究
Brad A Ryva,Zheng Zhou,Jaclyn M Goodrich et al.
Brad A Ryva et al.
Many studies implicate mitochondrial dysfunction in the development and progression of numerous chronic diseases. Mitochondria are responsible for most cellular energy production, and unlike other cytoplasmic organelles, mitochondria contai...
Stem cell development involves divergent thyroid hormone receptor subtype expression and epigenetic modifications in the amphibian intestine during metamorphosis [0.03%]
两栖动物肠上皮在变态发育过程中涉及甲状腺激素受体亚型的表达和表观遗传修饰
Takashi Hasebe,Kenta Fujimoto,Atsuko Ishizuya-Oka
Takashi Hasebe
In the amphibian intestine during metamorphosis, most of the larval epithelial cells undergo apoptosis, while a small number of the epithelial cells dedifferentiate into stem cells (SCs). The SCs actively proliferate and then newly generate...
About the editor [0.03%]
关于编辑器
Gerald Litwack
Gerald Litwack
Attila Hunyadi,Orinhamhe G Agbadua,Gábor Takács et al.
Attila Hunyadi et al.
The term "scavengome" refers to the chemical space of all the metabolites that may be formed from an antioxidant upon scavenging reactive oxygen or nitrogen species (ROS/RNS). This chemical space covers a wide variety of free radical metabo...
Molecular docking approaches and its significance in assessing the antioxidant properties in different compounds [0.03%]
分子对接方法及其在评估不同化合物抗氧化性能中的意义
Neha Srivastava,Prekshi Garg,Anurag Singh et al.
Neha Srivastava et al.
In the last few years, the significance of antioxidant compounds and their properties has attracted great interest from the scientific community. The role of an antioxidant in managing & regulating oxidative stress and also in the protectio...
Hydrogen peroxide detoxification through the peroxiredoxin/thioredoxin antioxidant system: A look at the pancreatic β-cell oxidant defense [0.03%]
过氧化氢的解毒作用通过过氧化物酶/硫氧还蛋白抗氧化系统：胰腺β细胞抗氧化防御研究
Jennifer S Stancill,John A Corbett
Jennifer S Stancill
Reactive oxygen species (ROS), such as hydrogen peroxide, are formed when molecular oxygen obtains additional electrons, increasing its reactivity. While low concentrations of hydrogen peroxide are necessary for regulation of normal cellula...
Protein l-isoAspartyl Methyltransferase (PIMT) and antioxidants in plants [0.03%]
植物中的蛋白l-异瓜氨酸甲基转移酶(PIMT)和抗氧化剂
Shraboni Ghosh,Manoj Majee
Shraboni Ghosh
All life forms, including plants, accumulate reactive oxygen species (ROS) as a byproduct of metabolism; however, environmental stresses, including abiotic stresses and pathogen attacks, cause enhanced accumulation of ROS in plants. The inc...