Estimation of concentration of chosen adhesive factors in suprarenal tumours of 'incidentaloma' type [0.03%]
肾上腺-incidentaloma型肿瘤中多种粘附分子的浓度测定及意义分析
Krzysztof Kołomecki,Henryk Stepień,Tomasz Stepień et al.
Krzysztof Kołomecki et al.
The role of adhesive molecules in the pathogenesis of adrenal gland tumours formation remains unclear. Here we present the concentrations of soluble vascular cell adhesion molecule-1 (sVCAM-1) and soluble intracellular adhesion molecule-1 (...
Telomere length and hTERT expression in patients with colorectal carcinoma [0.03%]
结肠癌患者端粒长度和hTERT表达水平的研究
Robert Rosenberg,Ralf Gertler,Dominik Stricker et al.
Robert Rosenberg et al.
The stabilization of telomere length by telomerase activation is an important step in carcinogenesis. Quantification of the catalytic telomerase subunit hTERT (human Telomerase Reverse Transcriptase) is a new indirect measure for telomerase...
Genetic subtyping of renal cell carcinoma by comparative genomic hybridization [0.03%]
比较基因组杂交对肾细胞癌的遗传分类研究
Kerstin Junker,Gregor Weirich,Mahul B Amin et al.
Kerstin Junker et al.
The prognosis of renal cell carcinoma (RCC) varies dependent on histologic tumor subtypes. However, differentiation between RCC types may sometimes be difficult on histologic grounds alone. Furthermore, the prognostic value of histologic pa...
Antitumoral and antimetastatic effects of continuous particle-mediated cytokine gene therapy [0.03%]
连续颗粒介导的细胞因子基因治疗的抗肿瘤和抗转移效果
Arne Dietrich,Katja Kraus,Ute Brinckmann et al.
Arne Dietrich et al.
We established a mice tumor model to investigate the effects of continuous cancer gene therapy, including antigen-presenting cell (APC) engineering and local stimulation of the immune system. B16 melanoma or Lewis lung carcinoma cells were ...
Detection of circulating tumor cells in blood using an optimized density gradient centrifugation [0.03%]
采用优化的密度梯度离心法检测血液中的循环肿瘤细胞
Ralf Gertler,Robert Rosenberg,Katrin Fuehrer et al.
Ralf Gertler et al.
The aim of the study was to compare the new density gradient centrifugation system OncoQuick with the standard density gradient centrifugation system Ficoll for improved tumor cell enrichment in blood of tumor patients. Evaluation of OncoQu...
Estrogen receptor expression profile of disseminated epithelial tumor cells in bone marrow of breast cancer patients [0.03%]
乳腺癌患者骨髓中转移上皮肿瘤细胞的雌激素受体表达谱式分析
Nina Ditsch,Barbara Mayer,Michaela Rolle et al.
Nina Ditsch et al.
The estrogen receptor (ER) status in primary breast cancer represents an important prognostic factor and has a profound impact on therapeutic decisions. However, ER expression profile on disseminated breast cancer cells is largely unknown, ...
Minimal residual disease in bone marrow and peripheral blood of patients with metastatic breast cancer [0.03%]
转移性乳腺癌患者骨髓和外周血中的最小残余疾病
Joachim Bischoff,Robert Rosenberg,Michael Dahm et al.
Joachim Bischoff et al.
The presence of occult micrometastases in bone marrow (BM) of patients with early breast cancer increases the risk of relapse. Detection of circulation tumor cells in peripheral blood (PB) may also influence the patient's prognosis. Few dat...
Clinical implications of the EGF receptor/ligand system for tumor progression and survival in gastrointestinal carcinomas: evidence for new therapeutic options [0.03%]
表皮生长因子受体/配基系统在胃肠道癌的肿瘤发生发展及生存中的临床意义：提示新的治疗选择的证据
Reinhard Kopp,Elisabeth Rothbauer,Maximilian Ruge et al.
Reinhard Kopp et al.
The epidermal growth factor (EGF) receptor and its various ligands (EGF, TGF-alpha, amphiregulin, heparin-binding (HB)-EGF, heregulin, betacellulin) seem to be involved in the growth regulation of intestinal mucosa and might be related to t...
Ronald Kates,Manfred Schmitt,Nadia Harbeck
Ronald Kates
Adequate staging procedures are the prerequisite for individualized therapy concepts in cancer, particularly in the adjuvant setting. Molecular staging markers tend to characterize specific, fundamental disease processes to a greater extent...
Minimal residual disease in breast cancer and gynecological malignancies: phenotype and clinical relevance [0.03%]
乳腺癌和妇科恶性肿瘤中的最小残留病灶：表型及临床意义
Frigga Roggel,Stefan Hocke,Kristina Lindemann et al.
Frigga Roggel et al.
In breast cancer, about 35% of patients without any clinical signs of overt distant metastases already have disseminated tumor cells in bone marrow aspirates at the time of primary therapy. A significant prognostic impact of these dissemina...