Sonja Schelhaas,Michael Schäfers
Sonja Schelhaas
As tumors represent one of the most common causes of death in developed countries, it is of utmost importance to understand the (molecular) mechanisms underlying tumor progression. On this basis, cancer diagnosis and therapy can be improved...
Joanna Napp,Andrea Markus,Frauke Alves
Joanna Napp
Optical imaging is crucial in preclinical evaluation of tumor development, progression, and therapies, due to its low cost, versatility, sensitivity, and capability of real-time monitoring. The main in vivo imaging techniques include fluore...
Wilfried Reichardt,Andreas B Schmidt,Dominik von Elverfeldt
Wilfried Reichardt
The evolving possibilities of molecular imaging (MI) are fundamentally changing the way we look at cancer, with imaging paradigms now shifting away from basic morphological measures toward the longitudinal assessment of functional, metaboli...
Youngho Seo,Elena M Zannoni
Youngho Seo
Molecular imaging enables both spatial and temporal understanding of the complex biological systems underlying carcinogenesis and malignant spread. Single photon emission computed tomography (SPECT) is a versatile nuclear imaging technique ...
Daniel Truhn,Sven Nebelung
Daniel Truhn
In this chapter, we explore the landscape of artificial intelligence and radiomics in molecular oncology imaging. Advances in molecular imaging methods offer powerful insights into tumor biology but generate complex data beyond the capabili...
Michel Eisenblätter,Moritz Wildgruber
Michel Eisenblätter
Tissue has characteristic properties when it comes to light absorption and scattering. For optical (OI) and optoacoustic imaging (OAI) these properties can be utilised to visualise endogenous chromophores, such as the oxygenation state of h...
Microbubble Contrast Agents for Molecular Ultrasound Imaging of Tumor Vasculature [0.03%]
肿瘤血管分子超声成像的微气泡对比剂研究进展
Alexander L Klibanov
Alexander L Klibanov
Molecular ultrasound imaging was proposed more than two decades ago. The ultrasound contrast agents used for selective targeting of vascular biomarkers of disease are formulated as gas microbubbles surrounded by a thin shell.Microbubbles ar...
18F-Labeled Small-Molecule and Low-Molecular-Weight PET Tracers for the Noninvasive Detection of Cancer [0.03%]
18F标记的小分子和低分子量正电子发射断层扫描示踪剂的非侵入性癌症检测中的应用
Christopher M Waldmann,Klaus Kopka,Stefan Wagner
Christopher M Waldmann
Non-invasive molecular imaging of cancer by means of the hybrid imaging modalities PET/CT and PET/MRI represents a powerful diagnostic tool in modern nuclear medicine. Radiotracers labeled with the prominent positron-emitter fluorine-18 are...
Hans-Jürgen Pietzsch,Cristina Müller,Roger Schibli et al.
Hans-Jürgen Pietzsch et al.
Single-photon emission computed tomography (SPECT) is the state-of-the-art imaging modality in nuclear medicine, although only a few new SPECT tracers have become available in the past 20 years. Critical for the future success of SPECT is t...
Dorde Komljenovic,Philipp Biegger,Helen Abeln et al.
Dorde Komljenovic et al.
Magnetic resonance imaging is characterized by high spatial resolution and unsurpassed soft tissue discrimination. Development and characterization of both intrinsic and extrinsic magnetic resonance (MR) imaging probes in the last decade ha...