Monique R Bernsen,Marcel van Straten,Gyula Kotek et al.
Monique R Bernsen et al.
Imaging in Oncology is rapidly moving from the detection and size measurement of a lesion to the quantitative assessment of metabolic processes and cellular and molecular interactions. Increasing insights into cancer as a complex disease wi...
Daniela Pfeiffer,Franz Pfeiffer,Ernst Rummeny
Daniela Pfeiffer
Since their discovery by Wilhelm Conrad Röntgen in 1895, X-rays have become the most widely available, typically fastest, and usually most cost-effective medical imaging modality today. From the early radiographic approaches using X-ray fi...
Computational Analysis of DNA and RNA Sequencing Data Obtained from Liquid Biopsies [0.03%]
基于液体活检数据的DNA和RNA测序数据的计算分析方法研究
Francesco Marass,Francesc Castro-Giner,Barbara Maria Szczerba et al.
Francesco Marass et al.
Next-generation sequencing of DNA and RNA obtained from liquid biopsies of cancer patients may reveal important insights into disease progression and metastasis formation, and it holds the promise to enable new methods for noninvasive scree...
Extracellular Vesicles: Recent Developments in Technology and Perspectives for Cancer Liquid Biopsy [0.03%]
外泌体：技术最新进展及癌症液体活检新视角
Irina Nazarenko
Irina Nazarenko
Extracellular micro- and nanoscale membrane vesicles produced by different cells progressively attract the attention of the scientific community. They function as mediators of intercellular communication and transport genetic material and s...
Sabrina Müller,Florian Janke,Steffen Dietz et al.
Sabrina Müller et al.
Lung cancer is the number one cause of cancer-related mortality worldwide. To improve disease outcome, it is crucial to implement biomarkers into the clinics which assist physicians in their decisions regarding diagnosis, prognosis, as well...
Gitte Brinch Andersen,Jörg Tost
Gitte Brinch Andersen
Deregulation of microRNA expression has been shown to play an important role in human malignancies. The identification of circulating-free miRNAs in biofluids a decade ago led to great enthusiasm and motivation to develop non-invasive tests...
Joana Vidal,Alvaro Taus,Clara Montagut
Joana Vidal
An accurate profiling of the genomic landscape is mandatory to establish the best clinical and therapeutic approach for patients with solid malignancies. Moreover, tumor cells constantly adapt to external pressures-i.e., systemic treatment-...
Alexandre Harlé
Alexandre Harlé
Colorectal cancer is one of the leading cause of death by cancer worldwide in both men and women. Liquid biopsy belongs nowadays to the landscape of cancer management biological tools. In this chapter, we will describe and discuss the actua...
Florian Clatot
Florian Clatot
In only few years, circulating tumor DNA (ctDNA) in breast cancer has moved from purely fundamental research to nearby daily use for treatment selection and drug-resistance assessment. Indeed, technical advances and widespread use of next-g...
Capturing Tumor Heterogeneity and Clonal Evolution by Circulating Tumor DNA Profiling [0.03%]
通过循环肿瘤DNA检测捕捉肿瘤异质性和克隆演化
Florian Scherer
Florian Scherer
Most malignancies are characterized by remarkable molecular heterogeneity. The understanding of genetic and epigenetic processes underlying tumor heterogeneity has become increasingly important for the clinical management of cancer patients...