DNA Damage and Skin Injuries Caused by Ionizing Radiation and Strategies for Wound Healing [0.03%]
电离辐射引起的DNA损伤及皮肤损伤和促伤口愈合策略
Olga F Senyuk,Xiaohong Wang,Hadrian Nassabi et al.
Olga F Senyuk et al.
Exposure to ionizing radiation can cause severe skin damage, leading to the development of cutaneous radiation syndrome. Wound healing of radiation-induced skin injuries proceeds in defined phases that depend on the intensity and type of ra...
Inorganic Polyphosphate and Alkaline Phosphatase/Adenylate Kinase: Key Components of the Physiological ATP-Dependent Wound Repair and Mode of Action [0.03%]
无机多聚焦磷酸盐和碱性磷酸酶/腺苷酸激酶：生理性的ATP依赖的伤口修复的关键成分及其作用方式
Heinz C Schröder,Meik Neufurth,Xiaohong Wang et al.
Heinz C Schröder et al.
Platelets play a crucial role in physiological wound healing, providing the energy required for this highly ATP-dependent repair/regeneration process. The formation of these cell fragments, which accumulate the energy-rich polymer inorganic...
Advanced Strategies in the Repair of Alveolar Cleft Defects: Biological Approaches, Biomaterials, and Future Perspectives [0.03%]
高级腭裂缺损修复策略：生物方法、生物材料及未来展望
Muhammad Ruslin,Carolina Stevanie,Andi Tajrin
Muhammad Ruslin
The repair of alveolar cleft defects remains a formidable challenge in craniofacial surgery, with implications for dental arch continuity, tooth eruption, speech, and facial aesthetics. Traditional bone grafting methods (especially iliac cr...
Mucosal Wound Repair: Reinforcement of Respiratory Mucus Barrier Function by Inorganic Polyphosphate [0.03%]
黏膜创伤修复：无机多磷酸对呼吸系统粘液屏障功能的强化作用
Xiaohong Wang,Heinz C Schröder,Meik Neufurth et al.
Xiaohong Wang et al.
Epithelial cell damage affects not only the skin, which covers the external surface of the human body, but also the non-keratinized epithelia, the mucosa, that lines the surfaces of internal organs, including the nasopharynx and lungs. This...
Mark Rabinovich,Elsa W Böhm,Yue Ruan et al.
Mark Rabinovich et al.
The corneal epithelium, a stratified squamous non-keratinized layer of 50-60 μm thickness, forms the outermost barrier of the cornea and provides both optical clarity and protection against trauma, infection, and fluid imbalance. It plays ...
Chronic Wound Healing: Breakthrough Strategies Based on Inorganic Polyphosphate [0.03%]
基于无机焦磷酸的慢性伤口愈合创新策略研究进展
Werner E G Müller,Meik Neufurth,Hadrian Nassabi et al.
Werner E G Müller et al.
Wound healing is a highly energy-dependent process. Physiologically, the required metabolic energy is supplied by the blood platelets in the form of inorganic polyphosphate, which serves as a source for the generation of the energy carrier ...
Ekaterina V Kulakovskaya,Tatiana V Kulakovskaya
Ekaterina V Kulakovskaya
Inorganic polyphosphate (polyP), a linear polymer of orthophosphoric acid residues, is essential for living cells from bacteria to humans. It forms complexes with metal ions, DNA, and polyhydroxybutyrate. The interaction of polyP with prote...
Collagen from Marine Sources for Potential Application in Wound Treatment [0.03%]
来源于海洋的胶原蛋白在伤口治疗中的潜在应用研究
Eleonora Tassara,Marco Giovine,Marina Pozzolini
Eleonora Tassara
Collagen is a biocompatible, biodegradable, and low-immunogenic protein, making it an ideal candidate for regenerative medicine. Due to ethical/religious concerns and the risk of disease transmission from traditional terrestrial mammal sour...
Energy Metabolic Regulatory Materials Promote Wound Healing in Senescent Environment [0.03%]
能量代谢调控材料促进衰老环境下的伤口愈合
Xuetong Wang,Tingbin Zhang,Huan Zhou et al.
Xuetong Wang et al.
Chronic wounds, pathological states failing to heal promptly, are especially prevalent among the elderly. This impaired healing in the senescent tissue is predominately attributed to the accumulation of senescent cells and a concomitant dec...
Polyphosphate in Antiviral Protection: A Polyanionic Inorganic Polymer in the Fight Against Coronavirus SARS-CoV-2 Infection [0.03%]
多磷酸在抗病毒保护中的作用：对抗冠状病毒SARS-CoV-2感染的多阴离子无机聚合物
Werner E G Müller,Xiaohong Wang,Meik Neufurth et al.
Werner E G Müller et al.
Polyanions as polymers carrying multiple negative charges have been extensively studied with regard to their potential antiviral activity. Most studies to date focused on organic polyanionic polymers, both natural and synthetic. The inorgan...