Ethical considerations with using placebo treatments and effects in clinical practice [0.03%]
临床实践中使用安慰剂治疗及效应的伦理考量
Leo Druart,Marco Annoni,Charlotte Blease
Leo Druart
Placebo effects have garnered increasing attention in recent decades. Research has demonstrated the existence of neurobiologic and neuropsychologic mechanisms underlying these effects, suggesting their genuine psychobiological nature. Harne...
Christina Emborg,Simple Futarmal Kothari,Nanna Brix Finnerup et al.
Christina Emborg et al.
Over the past decades, a growing number of clinical trials in neurologic conditions have failed to demonstrate superiority of active treatments over placebo. A key question in this context is whether an increase in placebo response can expl...
Kirsten Barnes,Kate Faasse,Andrew L Geers
Kirsten Barnes
In late 2019, reports of pneumonia from an unknown cause marked the beginning of an unprecedented health crisis with far-reaching societal consequences. The ensuing global pandemic placed immense strain on healthcare systems, disrupted econ...
Duncan Sanders,Andrew Weiss,Damien Finniss
Duncan Sanders
Placebo effects are inherent in all healthcare encounters and are underpinned by the therapeutic context. Every therapeutic context is rich in its ability to initiate and maintain placebo mechanisms, with the healthcare provider clinician i...
Jens Gaab
Jens Gaab
The relationship between psychotherapy and placebo has been debated ever since the clinical dawn of both interventions, even though they differ considerably in appearance and application. Two positions can be distinguished: On the one hand,...
Hypoxia [0.03%]
低氧诱导因素及其信号转导机制研究进展与展望
Diletta Barbiani,Eleonora Volpato,Francesco Pagnini
Diletta Barbiani
Placebo and nocebo effects are particularly relevant in hypoxia research. Studies performed at high-altitude environments have shown that placebos can partially mimic the effects of oxygen (O2) and compensate for some of the imbalances at t...
Fabrizio Benedetti,Aziz Shaibani
Fabrizio Benedetti
In this chapter, we will review the available literature on the nature of the placebo effect in conditions that are not well studied in terms of their response to the placebo intervention such as fatigue in general and in the context of mya...
Marcel Wilhelm,Winfried Rief,Stefan Salzmann
Marcel Wilhelm
This chapter delves into the multifaceted role of placebo effects in mental disorders, highlighting their impact on treatment outcomes across a spectrum of conditions, including depression, anxiety, schizophrenia, and bipolar disorder. Plac...
Dimos-Dimitrios Mitsikostas,Christina Deligianni
Dimos-Dimitrios Mitsikostas
As in the treatment of other pain conditions, the placebo and nocebo effects play an important role in the treatment of primary headache disorders, which are the most prevalent neurologic conditions worldwide with enormous personal and soci...
Placebo effects and emotion regulation: conceptual and neural similarities and differences [0.03%]
安慰剂效应与情绪调节：概念及神经机制的异同点分析
Ke Bo,Tor D Wager
Ke Bo
Placebo effects are a family of diverse effects that tap into the brain and body's latent endogenous therapeutic potential. Unlike placebo responses, which can reflect statistical artifacts and natural history, placebo effects are driven by...