Machelle T Pardue
Machelle T Pardue
Michael J Aminoff,François Boller,Dick F Swaab
Michael J Aminoff
Jodi Hwang,Hossein Ameri
Jodi Hwang
Fundus autofluorescence (FAF) is a widely utilized method of imaging the retina. It provides a quick and noninvasive method to assess the health of the photoreceptor and retinal pigment epithelium. FAF enables topographic mapping of the met...
Jan Kremers,Cord Huchzermeyer,Anneka Joachimsthaler
Jan Kremers
The electroretinogram (ERG) is an important assay for retinal physiology. This noninvasive recording can be used for basic and disease-related research. This chapter addresses ERGs, recorded in humans and nonhuman primates, for assessing re...
Austin Roorda
Austin Roorda
Scanning light imaging systems are broadly useful in many applications, especially when applied to ophthalmoscopy and vision science. This chapter aims to explain how and why they are useful. It starts by covering the basic principles of sc...
Xue DU,Holly Y Chen
Xue DU
Human pluripotent stem cells, including embryonic stem cells and induced pluripotent stem cells, can be directed to self-organize into three-dimensional retinal organoids that recapitulate the development, cellular architecture, and key fun...
Benjamin W J Ng,Robert E Maclaren,Jasmina Cehajic-Kapetanovic
Benjamin W J Ng
Optogenetics is the process of photosensitizing cells and thereby controlling their activity with light. The discovery of channelrhodopsins has allowed for a reversible, spatiotemporally precise method to activate or silence specific target...
Guoqin Wei,Helena Pham,Emma Randall-Jarrard et al.
Guoqin Wei et al.
Neurodegenerative diseases of the retina result from diverse insults, including genetic mutations, metabolic deficiencies, vascular compromise, and inflammatory injury. These processes converge on dysfunction of the neurovascular unit, wher...
Vision restoration: From prostheses to genetic-based brain-machine interfaces [0.03%]
视觉修复：从辅助设备到基于基因的脑机接口
Ignacio Alcala,Erwan Desailly,Fabrice Arcizet et al.
Ignacio Alcala et al.
Visual restoration is the major challenge for brain-machine interfaces because vision requires perception of images containing a high number of pixels that have to be presented at a high refresh rate. Classically, visual prostheses were mad...
Jessica Wang,Tina Felfeli,Brian G Ballios
Jessica Wang
Stem cell therapy presents a new solution to cure degenerative diseases of the retina, which normally have limited ability to regenerate after injury. Stem cells are cells capable of self-renewal and differentiation into more specialized ce...