Epstein-Barr Virus: From the Detection of Sequence Polymorphisms to the Recognition of Viral Strains [0.03%]
EB病毒：从检测序列多态性到识别病毒株
Rémy Poirey,Bowen Bai,Hao Li et al.
Rémy Poirey et al.
The Epstein-Barr virus is etiologically linked with the development of benign and malignant diseases, characterized by their diversity and a heterogeneous geographic distribution across the world. The virus possesses a large genome that enc...
Anthony Epstein
Anthony Epstein
An account is given of the experiences and events which led to a search being undertaken for a causative virus in the recently described Burkitt's lymphoma and of the steps which ultimately culminated in the discovery of the new human herpe...
Elizabeth M Anderson,Alfred J Saah,Joseph E Tota
Elizabeth M Anderson
Human papillomavirus (HPV) vaccination effectively reduces the risk of HPV-attributable cancers, including cervical, vulvar, vaginal, anal, oropharyngeal, and other head and neck cancers. Concerns for a lower-than-expected vaccine impact, a...
DNA Methylation in Cervical Intraepithelial Neoplasia and Cervical Cancer: Triage and Management [0.03%]
宫颈鳞状上皮内病变和宫颈癌中DNA甲基化研究：分流和管理策略
Mila S Griffioen,Flavia Runello,Renske D M Steenbergen
Mila S Griffioen
This chapter discusses the role of DNA methylation, an epigenetic mechanism that regulates gene expression, as a key event in cervical carcinogenesis, and highlights its potential as a biomarker for detecting cervical cancer and high-grade ...
Human Papillomavirus Screening: Design and Targeting of Human Papillomavirus Genotypes [0.03%]
人乳头瘤病毒分型筛查的设计及目标型别检测
Joakim Dillner
Joakim Dillner
In 2018, there were globally about 350,000 deaths from cervical cancer, despite the fact that the disease can be prevented by screening and in spite of the fact that highly effective human papillomavirus (HPV) tests became available some 25...
Laura Burney Ellis,Maria Kyrgiou,Anna-Barbara Moscicki
Laura Burney Ellis
The microbiome describes the collection of genes derived from microorganisms that live in body systems. After the discovery of Lactobacilli as important for vaginal health, the vaginal microbiome was initially binarily classified into healt...
Marta Del Pino
Marta Del Pino
Human papillomavirus (HPV) infection is the necessary cause of cervical cancer (CC) and other HPV-related malignancies, yet by itself is not sufficient for malignant progression. A myriad of co-factors influences the risk that an HPV infect...
Immune Responses to Human Papillomavirus After Infection and Vaccination [0.03%]
人乳头瘤病毒感染和接种疫苗后的免疫反应
Hannah S Newton,Daniel B Zwick,Troy J Kemp et al.
Hannah S Newton et al.
Human papillomavirus (HPV) is one of the most common sexually transmitted infections globally, infecting most sexually active individuals. HPV infection is usually asymptomatic and often transient; however, some infections can persist and c...
Heather M Long,Graham S Taylor
Heather M Long
Epstein-Barr virus (EBV) infects nearly every individual whereupon it persists for life under the control of a broad immune response. EBV provides a valuable system for understanding human T cell immunology. It is genetically stable and exp...
Laura F Walsh,Rena R Xian,Richard F Ambinder
Laura F Walsh
Epstein-Barr virus (EBV) DNA in blood is associated with many diseases, though most often it is not linked to any disease. EBV DNA can be measured in whole blood, PBMCs, serum, or plasma. Using the most sensitive assays, viral DNA can be de...