Ronald A Arky
Ronald A Arky
It is just a century since Abraham Flexner was invited by the Carnegie Foundation to evaluate medical education in the U.S. and Canada. After a visit to all of the existing medical schools at that time, Flexner issued a report in 1910 that ...
Carol O Tacket
Carol O Tacket
Every year 1.6 million deaths occur due to diarrhea related to unsafe water and inadequate sanitation-the vast majority in children under 5 years old. Safe and effective vaccines against enteric infections could contribute to control of the...
Ian L Taylor
Ian L Taylor
On Monday, August 29, 2005 Hurricane Katrina passed east of New Orleans causing minimal damage to Tulane's Medical Center. Later that day, levees that protected the city failed and several feet of water entered the hospitals and school buil...
B Gardner Laurence
B Gardner Laurence
Bruce C Kone,Zhang Wenzhang,Yu Zhiyuan
Bruce C Kone
Gene transcription is highly regulated to ensure that specific genes are expressed at the appropriate times, places and levels in response to various genetic and environmental stimuli. Activation of some genes occurs by relief of basal repr...
Regulation of kidney function and metabolism: a question of supply and demand [0.03%]
肾脏功能和代谢的调节：供应与需求的问题
Roland C Blantz,Aihua Deng,Cynthia M Miracle et al.
Roland C Blantz et al.
Kidney blood flow and glomerular filtration rate (GFR) are maintained relatively constant by hormonal influences and by efficient autoregulation. However, the kidney remains at risk for ischemia and acute kidney injury. Increases in kidney ...
Robert G Luke
Robert G Luke
Chronic diabetic complications: the body's adaptive response to hyperglycemia gone awry? [0.03%]
慢性糖尿病并发症：高血糖引起的机体适应性反应异常吗？
Lawrence Chan,Tomoya Terashima,Mineko Fujimiya et al.
Lawrence Chan et al.
In the last two decades, diabetes mellitus has reached epidemic proportions in the United States. Most of the recent increase in prevalence of diabetes involves type 2 disease and is a result of an alarming increase in prevalence of obesity...
William W Hay Jr
William W Hay Jr
Fetal glucose metabolism depends on additive effects of fetal plasma glucose and insulin. Glucose-stimulated insulin secretion increases over gestation, is down-regulated by constant hyperglycemia, but enhanced by pulsatile hyperglycemia. I...
Jean E Robillard,Jeffrey L Segar
Jean E Robillard
The transition from the fetal to the extrauterine environment is associated with complex physiological adjustments and involves numerous cardiovascular, pulmonary, and metabolic adjustments to ensure successful adaptation to the postnatal l...