Stanley W Chapman,Donna C Sullivan,John D Cleary
Stanley W Chapman
The ideal antifungal agent remains an elusive goal for treatment of life-threatening systemic fungal infections. Such an agent would have broad antifungal activity, low rates of resistance, flexible routes of administration, few associated ...
Heart failure with a normal left ventricular ejection fraction: diastolic heart failure [0.03%]
左心室射血分数正常的心力衰竭：舒张性心力衰竭
William C Little
William C Little
A reduced left ventricular ejection fraction measured by echocardiography in a patient with clinical features of heart failure demonstrates that the patient has a cardiac abnormality and that the clinical picture is, in fact, due to heart f...
Hugh Calkins
Hugh Calkins
Background: Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD) is a genetic cardiomyopathy characterized by ventricular arrhythmias and structural abnormalities of the right ventricle (RV). The discovery of ...
Jules B Puschett
Jules B Puschett
The bufodienolides are natriuretic steroids, which also have the capacity to cause vasoconstriction, and are cardiac inotropes. Their mechanism of action appears to be related to their ability to inhibit Na+/K+ ATPase. The actions of one of...
Sharon Rounds,Qing Lu,Elizabeth O Harrington et al.
Sharon Rounds et al.
RhoA is an important modulator of endothelial monolayer permeability. Posttranslational carboxyl methylation of small GTPases, such as RhoA and Ras, regulates subcellular localization and GTPase activity, resulting in altered cellular funct...
Professionalism and accountability: the role of specialty board certification [0.03%]
专业与责任：专科委员会认证的作用
Christine K Cassel,Eric S Holmboe
Christine K Cassel
The black cholera comes to the central valley of America in the 19th century - 1832, 1849, and later [0.03%]
十九世纪美洲中部大平原的霍乱疫情——1832、1849及以后
Walter J Daly
Walter J Daly
In mid-19th Century, cholera was epidemic throughout the world. Small towns of the American Midwest were not spared. The disease was blamed on miasmas arising from local causes, so flight from affected localities were logical and common. Fl...
William W Stead,Neal R Patel,John M Starmer
William W Stead
A closed loop control process assures that a system performs within control limits. In closed loop control, the system's output feeds back directly to change the system's inputs. We describe an approach to planning and monitoring care that ...
Addiction in medicine [0.03%]
医学中的瘾癖问题
Robert L DuPont
Robert L DuPont