Cancer in the elderly [0.03%]
老年人的癌症治疗挑战
Nathan A Berger,Panos Savvides,Siran M Koroukian et al.
Nathan A Berger et al.
As the population expands, over the period from 2000 to 2050, the number and percentage of Americans over age 65 is expected to double. This population expansion will be accompanied by a marked increase in patients requiring care for disord...
Stephan L Kamholz
Stephan L Kamholz
The putative cardiovascular risks and benefits of the ingestion of wine and alcohol-containing spirits have been well publicized; however, less attention has been focused upon the health effects of wine and spirits consumption on the respir...
Peter M Howley
Peter M Howley
Certain human papillomaviruses (such as HPV-16 and HPV-18) are associated with specific anogenital cancers, most notably cervical cancer. These viruses encode two oncoproteins, E6 and E7, which are expressed in the HPV positive cancers. E7 ...
Paul F Bray
Paul F Bray
It is widely accepted that there is marked inter-individual variation in platelet function, although this has not been formally studied in large numbers of subjects. We have recruited and studied three large populations: one to characterize...
William N Hait,Jin-Ming Yang
William N Hait
Our laboratory discovered that p53 can regulate the sensitivity to cancer therapies by affecting three critical aspects of cancer pharmacology: 1). The expression of drug targets; 2). the access of drugs to intracellular targets; and the re...
Theodore E. Woodward Award: host-pathogen interactions in community-acquired urinary tract infections [0.03%]
Woodward奖：社区获得性泌尿系统感染中的宿主病原菌相互作用
Walter E Stamm
Walter E Stamm
Community-acquired urinary tract infections continue to be a significant source of morbidity and health care costs. In addition, community-acquired urinary tract infections are an excellent model for studying the interaction of the infectin...
Theodore E. Woodward Award: development of novel, EBV-targeted therapies for EBV-positive tumors [0.03%]
针对EBV阳性肿瘤的新型EBV靶向治疗手段的研发获奖报告
Shannon Kenney
Shannon Kenney
The near universal presence of EBV in certain tumors suggests that new EBV-based therapies could be developed for these malignancies. We have explored one EBV-based therapy that involves the purposeful induction of lytic EBV infection in tu...
David J Tweardy,Naijie Jing
David J Tweardy
Approximately half of all medical illnesses can be attributed to insufficient or excessive apoptosis. Apoptosis resistance is a cardinal feature of cancer, mediated in many instances, by signal transducer and activator of transcription (STA...
Laurence A Boxer
Laurence A Boxer
Severe congenital neutropenia (SCN) is a rare hematological disease characterized by a selective decrease in circulating neutrophils, bone marrow maturation arrest at the promyelocyte stage, and occurrence of infections. Studies of SCN pati...
President's address: mother was right: the health benefits of milk of magnesia [0.03%]
总统致辞：妈妈说的没错：镁乳的好处
Marshall A Wolf
Marshall A Wolf