S Kidokoro
S Kidokoro
Based on three-dimensional structure of proteins, a rational strategy to design the protein function by physical perturbation method was proposed and tested on one of the well-examined enzymes, thermolysin for higher catalytic activity. An ...
The neuronal basis of visual memory and imagery in the primate: a neurophysiological approach [0.03%]
神经元基础：灵长类动物视觉记忆和表象的神经生理学方法
K Nakahara,M Ohbayashi,H Tomita et al.
K Nakahara et al.
To understand the biological basis of memory is one of the most exciting frontiers of science. Single unit recording is a powerful method to investigate neuronal correlates of various brain functions such as memory in awake animals. Anatomi...
Review
Advances in biophysics. 1998:35:103-19. DOI: 1998
O Hikosaka
O Hikosaka
Action is the means by which we and animals survive. It consists of a complex combination of movements which are either innately endowed or acquired by learning. In this article, I propose a hypothesis on the relationship between the organi...
Review
Advances in biophysics. 1998:35:81-102. DOI: 1998
Y Fujiyoshi
Y Fujiyoshi
A high-resolution electron cryo-microscope equipped with a top-entry specimen stage has been refined by modifying a previously described superfluid helium stage. Instruments equipped with such a cryo-stage achieve a resolution of better tha...
Structure-mutation analysis of the ATPase site of Dictyostelium discoideum myosin II [0.03%]
Dictyostelium discoideum 动力蛋白II的ATP酶活性中心结构及其突变分析
N Sasaki,K Sutoh
N Sasaki
Three loop structures called the P-loop, switch I loop and switch II loop of myosin are major components of its ATPase site, and share structural and functional homology with the loop structures in other ATPases and GTPases such as kinesin ...
Review
Advances in biophysics. 1998:35:1-24. DOI: 1998
K Matsubara,S Ebina
K Matsubara
Carbohydrate gluing (which may have a carbohydrate-lectin binding mechanism) was first recognized as a major contributor in the supramolecular assembly of annelid giant Hb from the marine-worm P. aibuhitensis. Although this assembly obvious...
W Knoll,M Liley,D Piscevic et al.
W Knoll et al.
Surface plasmon optical techniques are described as sensitive tools that allow for the on-line characterization of supramolecular biofunctional architectures at solid/solution interfaces. After a short introduction into the fundamentals of ...
Novel biosensoric devices based on molecular protein hetero-multilayer films [0.03%]
基于分子蛋白异复合层膜的新颖生物传感器装置
A Diederich,M Lösche
A Diederich
We have developed a novel concept for the modification of technical surfaces with molecularly well-organized layers of bioorganic components. A molecular construction set has been used to implement this concept which is based on molecularly...
M Yamaki
M Yamaki
In situ functional assay of each ferritin molecule in single-layer 2D arrays for horse spleen apoferritin and recombinant horse L- and human H-apoferritins was conducted by observing the iron-cores formed in the arrays by TEM. The study of ...
The influence of protein and interfacial structure on the self-assembly of oriented protein arrays [0.03%]
蛋白质和界面结构对有序蛋白阵列自组装的影响
D E Leckband
D E Leckband
These results demonstrate the complexity of factors that impact the self-assembly of protein arrays via the specific binding to receptor-functionalized interfaces. Both the composition and colloidal properties of the protein and target memb...