Genetic and physiological regulation of non-homologous end-joining in mammalian cells [0.03%]
哺乳动物细胞中非同源末端连接的遗传及生理调节机制研究进展
Akira Tachibana
Akira Tachibana
Repair of DSBs is important to prevent chromosomal fragmentation, translocations and deletions. To investigate the process in NHEJ, we have established an in vitro system to clarify the measurement and analysis of the efficiency and the fid...
Illegitimate recombination mediated by double-strand break and end-joining in Escherichia coli [0.03%]
大肠杆菌中由双链断裂和非同源末端连接介导的非同源重组
Hideo Ikeda,Kouya Shiraishi,Yasuyuki Ogata
Hideo Ikeda
The frequency of illegitimate recombination has been measured by a lambdabio transducing phage assay during the induction of the E. coli lambda c1857 lysogen. Illegitimate recombination falls into two classes, short homology-independent and...
Studies and perspectives of calponin in smooth muscle regulation and cancer gene therapy [0.03%]
钙泊宁在平滑肌调控和癌症基因治疗的研究及展望
Katsuhito Takahashi,Hisako Yamamura
Katsuhito Takahashi
Fertilization and development initiation in orthodox and unorthodox ways: from normal fertilization to cloning [0.03%]
经典与非经典的受精与发育启动：从正常受精到克隆
Ryuzo Yanagimachi
Ryuzo Yanagimachi
Brain neurosteroids are 4th generation neuromessengers in the brain: cell biophysical analysis of steroid signal transduction [0.03%]
脑神经类固醇是第四代脑内神经信息传递分子：甾体信号转导的细胞生物物理分析
Suguru Kawato,Makoto Yamada,Tetsuya Kimoto
Suguru Kawato
O Gotoh
O Gotoh
Elucidation of interrelationships among sequence, structure, function, and evolution (FESS relationships) of a family of genes or gene products is a central theme of modern molecular biology. Multiple sequence alignment has been proven to b...
Induced potential model of muscular contraction mechanism and myosin molecular structure [0.03%]
肌肉收缩诱导电位模型和肌球蛋白分子结构
T Mitsui
T Mitsui
The proposed model is characterized by the constant r (Eq. 2-1), the induced potential (Fig. 1), two attached states of a myosin head (Fig. 1), the nonlinear elastic property of the crossbridge (Eq. 2-7), and the expression of U* (Eqs. 3-8 ...
S Osawa,Z H Su,C G Kim et al.
S Osawa et al.
The phylogenetic relationships of the carabid ground beetles have been estimated by analysing a large part of the ND5 gene sequences of more than 1,000 specimens consisting of the representative species and geographic races covering most of...
Ryanodine receptor isoforms in excitation-contraction coupling [0.03%]
钙诱导的钙释放及兴奋-收缩耦联中的ryanodine受体同工酶形式的功能差异
Y Ogawa,N Kurebayashi,T Murayama
Y Ogawa
Three genomically distinct isoforms of RyR are now known. RyR1 homologue is the primary isoform in skeletal muscles, whereas in cardiac muscles it is RyR2 homologue. RyR3 homologue occurs ubiquitously in many cells, but the biological funct...
Y Kagawa
Y Kagawa
The isolation of ATP synthase (F0F1) (82) and F0 (83) 34 years ago finally revealed that F0F1 is a motor composed of F0 (ion-motor, abc subunits) and F1 (ATP-motor, alpha 3 beta 3 gamma delta epsilon subunits) (Fig. 1). The single molecule ...