Illegitimate recombination mediated by double-strand break and end-joining in Escherichia coli [0.03%]
大肠杆菌中由双链断裂和末端连接介导的非同源重组
Hideo Ikeda,Kouya Shiraishi,Yasuyuki Ogata
Hideo Ikeda
The frequency of illegitimate recombination has been measured by a lambda bio transducing phage assay during the induction of the E. coli lambda cI857 lysogen. Illegitimate recombination falls into two classes, short homology-independent an...
Review
Advances in biophysics. 2004:38:3-20. DOI: 2004
Molecular mechanism of vde-initiated intein homing in yeast nuclear genome [0.03%]
酵母核基因组中vde诱导的intein归巢分子机制
Tomoyuki Fukuda,Yuri Nagai,Yoshikazu Ohya
Tomoyuki Fukuda
In Saccharomyces cerevisiae, VMAI intein encodes a homing endonuclease termed VDE which is produced by an autocatalytic protein splicing reaction. VDE introduces a DSB at its recognition sequence on intein-minus allele, resulting in the lat...
Atsuko Gyohda,Nobuhisa Furuya,Akiko Ishiwa et al.
Atsuko Gyohda et al.
Conservative site-specific recombination plays key roles in creating biological diversity in prokaryotes. Most site-specific inversion systems consist of two recombination sites and a recombinase gene. In contrast, the shufflon multiple inv...
Transposition mechanisms and biothechnology applications of the medaka fish tol2 transposable element [0.03%]
斑马鱼Tol2转座子的转座机制及其生物技术应用
Akihiko Koga
Akihiko Koga
The Tol2 element of the medaka fish is a member of the hAT (hobo/Activator/Tam3) transposable element family. About 20 copies are present in the medaka fish genome and, unlike many other hAT family elements, virtually all the copies are aut...
Genetics and epigenetics in flower pigmentation associated with transposable elements in morning glories [0.03%]
与转座元件相关的牵牛属花卉着色的遗传和表观遗传学
Shigeru Iida,Yasumasa Morita,Jeong-Doo Choi et al.
Shigeru Iida et al.
Among the genus Ipomoea, three morning glories, I. nil the Japanese morning glory), I. purpurea (the common morning glory), and I. tricolor, were domesticated well for floricultural plants, and many spontaneous mutants displaying various fl...
Intermediate molecules generated by transposase in the pathways of transposition of bacterial insertion element 1S3 [0.03%]
细菌IS3插入序列转位途径中转座酶生成的中间分子
Eiichi Ohtsubo,Hiroshi Minematsu,Ken Tsuchida et al.
Eiichi Ohtsubo et al.
Gpt delta transgenic mouse: A novel approach for molecular dissection of deletion mutations in vivo [0.03%]
Gpt delta转基因小鼠：一种新的体内缺失突变分子分析方法
Takehiko Nohmi,Ken-Ichi Masumura
Takehiko Nohmi
Human genome is continuously exposed to various DNA damaging agents including reactive oxygen species. Of various forms of DNA damage, double-strand breaks (DSBs) in DNA are the most detrimental because of the mutagenicity and cytotoxicity....
Cell death promoted by homologous DNA interaction from bacteria to humans [0.03%]
从细菌到人类由同源DNA相互作用促进的细胞死亡
Kohji Kusano
Kohji Kusano
Pairing between homologous DNA controls cellular functions including double-strand break repair, mitotic recombination, and progression of DNA replication forks, as well as chiasma formation during meiosis. Here I summarize that homologous ...
Nijmegen breakage syndrome and DNA double strand break repair by NBS1 complex [0.03%]
与NBS1复合体介导的DNA双链断裂修复相关的Nijmegen小体型综合征
Shinya Matsuura,Junya Kobayashi,Hiroshi Tauchi et al.
Shinya Matsuura et al.
The isolation of the NBS1 gene revealed the molecular mechanisms of DSB repair. In response to DNA damage, histone H2AX in the vicinity of DSBs is phosphorylated by ATM. NBS1 then targets the MRE11/RAD50 complex to the sites of DSBs through...
The function of RecQ helicase gene family (especially BLM) in DNA recombination and joining [0.03%]
RecQ解旋酶基因家族（尤其是BLM）在DNA重组和连接中的功能
Hideo Kaneko,Toshiyuki Fukao,Naomi Kondo
Hideo Kaneko
Bloom syndrome is a rare autosomal recessive genetic disorder characterized by lupus-like erythematous telangiectasias of the face, sun sensitivity, stunted growth, and immunodeficiency. Chromosome instability syndromes have a common featur...