CHLOROQUINE DOES NOT CANCEL E1A+cHa-Ras TRANSFORMANTS’ DEATH INDUCED BY mTOR KINASE INHIBITOR pp242 [0.03%]
氯喹不能消除mTOR激酶抑制剂pp242诱导的E1A+Ha-ras转化细胞死亡现象
T V Bykova,S G Zubova,E Yu Kochetkova et al.
T V Bykova et al.
We have studied the dependence of cell viability on cell autophagy in control and senescent E1A+cHa-Ras transformed rat embryo fibroblasts. pp242, a TORC1/C2 kinase inhibitor, was used as a trigger of cell autophagy. Cell senescence was ind...
MEK/ERK-PATHWAY IS REQUIRED TO MAINTAIN CYTOPROTECTIVE AUTOPHAGY PROCESS IN IRRADIATED E1A+cHa-Ras TRANSFORMANTS [0.03%]
MEK/ERK信号途径维持E1A+cHa-Ras转化细胞放射后细胞保护作用的自噬过程所必需
E Yu Kochetkova,G I Blinova,S G Zubova et al.
E Yu Kochetkova et al.
Autophagy is a conservative process of misfolded protein and damaged organelle degradation that serves to support cellular viability. Autophagy is often induced in response to stress, DNA damage, retinoids, starvation and growth factor with...
EVALUATION OF EFFECTIVENESS OF SYNCHRONIZATION METHODS OF CELL DIVISION IN YEAST SACCHAROMYCES CEREVISIAE [0.03%]
评估酵母Saccharomyces cerevisiae细胞分裂同步化方法的有效性
A S Zhuk,E I Stepchenkova,Yu I Pavlov et al.
A S Zhuk et al.
Synchronization of cell division in cultures of yeast Saccharomyces cerevisiae is widely used in research on the regulation of gene expression and biochemical processes in eukaryotes at different stages of the cell cycle. Here, we compare t...
CHLOROQUINE DOES NOT CANCEL E1A+cHa-Ras TRANSFORMANTS’ DEATH INDUCED BY mTOR KINASE INHIBITOR pp242 [0.03%]
PP242诱导的E1A和c-Ha-ras转化细胞凋亡不受氯喹的影响
T V Bykova,S G Zubova, et al.
T V Bykova et al.
We have studied the dependence of cell viability on cell autophagy in control and senescent E1A+cHa-Ras transformed rat embryo fibroblasts. pp242, a TORC1/C2 kinase inhibitor, was used as a trigger of cell autophagy. Cell senescence was ind...
RECOVERY OF DIVISION PROCESS IN BACTERIAL CELLS AFTER INDUCTION OF SulA PROTEIN WHICH IS RESPONSIBLE FOR CYTOKINESIS ARREST DURING SOS-RESPONSE [0.03%]
负责SOS反应时细胞分裂停止的SulA蛋白诱导后的恢复过程研究
A D Vedyaykin,A V Sabantsev,I E Vishnyako et al.
A D Vedyaykin et al.
SOS-response is an important tool of bacteria intended to protect their genome and thereby allow them to survive under adverse conditions. Recently SOS-response is considered to enhance mutagenesis and thus help bacteria acquire antibiotic ...
RSH ANTIOXIDANTS INCREASE INTRACELLULAR ROS LEVEL AND PROLIFERATION OF SP2/0 MYELOMA CELLS IN SERUM-FREE MEDIUM [0.03%]
无血清培养体系中抗坏血酸茋胺酯类抗氧化剂促进SP2/0骨髓瘤细胞内活性氧水平升高及增殖
V Yu Tabakov,N N Veiko,V V Chestkov et al.
V Yu Tabakov et al.
At present research we have demonstrated the link between introducing of low molecular weight RSH-antioxidants (N-acetylcysteine, glutathione) into serum-free medium composition, reactive oxygen species (ROS) generation and mouse myeloma SP...
INFLUENCE OF INFLUENZA A VIRUS AND BACTERIAL LIPOPOLYSACCHARIDE ON PROLIFERATION AND GENE EXPRESSION OF CYTOKINES AND OTHER CELLULAR FACTORS IN CELLS OF ESTABLISHED ENDOTHELIAL CELL LINE ECV-304 [0.03%]
流感病毒和细菌脂多糖对已建立内皮细胞系ECV-304细胞增殖及多种细胞因子基因表达的影响
S S Smirnov,M M Pisareva,T D Smirnova et al.
S S Smirnov et al.
Change of state of endothelial cells occurs under the action of viral infection and bacterial lipopolysaccharide (LPS) that leads to cell dysfunction. Therefore, the aim of the current study was to investigate the effect of LPS from Escheri...
INFLUENCE OF HDAC INHIBITOR SODIUM BUTYRATE ON THE EXPRESSION OF DNA REPAIR GENES Rad51 AND XRCC5 IN mEras-Waf1+/+ AND mEras-Waf1–/– [0.03%]
HDAC抑制剂钠丁酸对DNA修复基因Rad51和XRCC5表达的影响
A N Kukushkin,S B Svetlikova,V A Pospelov
A N Kukushkin
Mouse embryonal fibroblasts with knockout of CDKN1A gene encoding p21/Waf1 protein transformed by oncogenes E1A and cHa-ras (mEras-Waf1–/– cell line) have been used to assess the level of DNA repair genes expression — Rad51 and XRCC5 aft...
L A Tashireva,K O Zavgorodskaya,V M Perelmuter
L A Tashireva
It is well known that inflammatory infiltrates in many cases present in the tumor tissue. In addition, to date, convincing evidence for its predictive value for different types of cancer. To the cells of the adaptive immune system, until re...
Review
Tsitologiia. 2016;58(12):901-7. DOI: 2016
COMPARISON OF THE SHAPE OF RABBIT MESENCHYMAL STROMAL CELLS DURING FIVE PASSAGES AFTER PRODUCTION OF PRIMARY CULTURE [0.03%]
兔原代培养后的五代间充质干细胞形态学比较研究
Yu P Petrov,N V Tsupkina
Yu P Petrov
Cultivation of cells under artificial conditions is one of the necessary procedures when working with stem cells. At this stage, the cells lose control by the macroorganism, becoming independent systems. Therefore, during the passaging of t...
Comparative Study
Tsitologiia. 2017;59(1):62-8. DOI: 2017