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CHLOROQUINE DOES NOT CANCEL E1A+cHa-Ras TRANSFORMANTS’ DEATH INDUCED BY mTOR KINASE INHIBITOR pp242

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We have studied the dependence of cell viability on cell autophagy in control and senescent E1A+cHa-Ras transformed rat embryo fibroblasts. pp242, a TORC1/C2 kinase inhibitor, was used as a trigger of cell autophagy. Cell senescence was induced in the cells by... ...