SYNTHESIS OF NOVEL BITHIOPHENE-SUBSTITUTED HETEROCYCLES BEARING CARBONITRILE GROUPS [0.03%]
含碳腈基取代的新型稠二噻苯杂环类化合物的合成研究
Mohamed A Ismail,David W Boykin
Mohamed A Ismail
Symmetrical and unsymmetrical bithiophene-substituted heterocycles bearing carbonitriles including imidazo[1,2-a]pyridine, benzimidazole, and pyridine derivatives have been synthesized via different synthetic protocols. The bithiophene bis-...
John B Bremner,Michael J Kelso
John B Bremner
This paper reports the compact synthesis of two isomeric dual-action hybrid antimicrobials where the 13-position of the antibacterial berberine has been linked via 3'- and 4'-methylene bridges to INF55 (5-nitro-2-phenylindole), an inhibitor...
Synthesis of Chiral Aziridines through Decarboxylative Generation of Sulfur Ylides and their Reaction with Chiral Sulfinyl Imines [0.03%]
通过硫叶立德的脱羧生成与具有手性的亚磺酰亚胺反应合成具有手性的氮杂环氧烷类化合物
David C Forbes,Sampada V Bettigeri,Sejal R Amin et al.
David C Forbes et al.
Reaction of sulfur ylide with a series of aryl substituted chiral non-racemic sulfinyl imines afforded the corresponding aziridines in high yield and good stereoselection. The sulfur ylides were generated by the thermally induced decarboxyl...
A Survey of Solvents for the Conrad-Limpach Synthesis of 4-Hydroxyquinolones [0.03%]
康拉德-林帕赫合成4-羟基喹诺酮类溶剂的调查研究
Jean-Cristophe Brouet,Shen Gu,Norton P Peet et al.
Jean-Cristophe Brouet et al.
A study on the synthesis of a 4-hydroxyquinoline derivative using the Conrad-Limpach reaction led to the identification of inexpensive and user-friendly solvents for this thermal condensation.
Phytochemicals from Echinacea and Hypericum: A Direct Synthesis of Isoligularone [0.03%]
金丝桃和紫锥菊中的植物化学成分：异白杨仁素的直接合成法
George A Kraus,Jaehoon Bae,Junwon Kim
George A Kraus
Reaction of trienes with α,β-unsaturated aldehydes produces bicyclic products via a tandem Diels-Alder/ene reaction. The adduct from tiglic aldehyde was converted into isoligularone by conversion to a furan followed by benzylic oxidation.