Małgorzata Jakubiak,Monika Asztemborska
Małgorzata Jakubiak
In the 21st century, nanomaterials play an increasingly important role, being used in many sectors, including: agriculture, medicine, chemical, textile, electronics and energy industries. Traditional nanoparticle (NP) synthesis methods rely...
[Genetic and Molecular Pathomechanisms of Amyotrophic Lateral Sclerosis and Therapeutic Perspectives – Current State of Knowledge] [0.03%]
遗传和分子水平上的肌萎缩侧索硬化症病理机制及治疗前景-目前的研究成果综述
Krzysztof Kalkowski
Krzysztof Kalkowski
Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease leading to progressive degeneration of motor neurons, muscle weakness and respiratory failure. Despite intensive research, the pathomechanisms of ALS have not bee...
[The prolamellar body as a distinctive model for biological membranes: structure, function, and application perspectives] [0.03%]
[质膜体——生物膜的独特模型：结构、功能与应用前景]
Katarzyna Tratkiewicz,Joanna Wójtowicz,Alicja Bukat et al.
Katarzyna Tratkiewicz et al.
The prolamellar body (PLB) is a complex membrane structure found in plant etioplasts that exhibits a diamond-type cubic symmetry. The PLB features a unique architecture based on two independent aqueous channels of distinct geometries: the l...
[The importance and perspectives of antidepressant use in adjuvant therapy of glioma] [0.03%]
抗抑郁药在胶质瘤辅助治疗中的作用及展望
Agata Grabowska,Anna Bielecka-Wajdman
Agata Grabowska
Glioblastoma multiforme (GBM) is a malignant and most agressive brain tumor. However, the current treatment standards and the progress that has been made over the last years in imaging methods and surgical techniques for glioma have not res...
Halszka Ponamarczuk,Marcin Popielarski
Halszka Ponamarczuk
Meldonium functions as an inhibitor of γ-butyrobetaine hydroxylase, the enzyme responsible for catalyzing the biosynthesis of L-carnitine. By inhibiting mitochondrial β-oxidation of fatty acids under hypoxic conditions, meldonium exerts c...
[Selected aspects of the pathogenesis of depression and the mechanisms of antidepressant action of statins] [0.03%]
抑郁症发病机制的几个方面及他汀类抗抑郁作用机制
Bożena Gabryel
Bożena Gabryel
There is a bidirectional relationship between the occurrence of depressive disorders and cardiovascular diseases. Both depression can increase the risk of cardiovascular disease and patients with cardiovascular disease often suffer from dep...
Maciej Jończyk
Maciej Jończyk
The usefulness of computers in biological research has been identified already in the sixties of the twentieth century. Subsequent technical progress allowed development of high-throughput experimental methods in biology. Thanks to them, on...
Dariusz Stępkowski,Adam Jarmuła
Dariusz Stępkowski
For over 100 years, medicine has not developed an effective method for treating Alzheimer's disease (AD). Despite countless studies, successes have been rather modest. This situation requires a new approach. In the current article, the auth...
[Natural polysaccharides as drug delivery system in colorectal cancer therapy] [0.03%]
[天然多糖作为结直肠癌治疗的药物递送系统]
Zuzanna Senkowska,Julia Wojtkowicz,Katarzyna Owczarek et al.
Zuzanna Senkowska et al.
Natural polysaccharides are a promising material for the design of drug delivery systems (DDS). Due to their properties, such as biocompatibility, biodegradability, chemical modifiability, and specific interactions with target cells, polysa...
[The role of peroxisome proliferator-activated receptors (PPARs) in the male gonad and prostate] [0.03%]
过氧化物酶体增殖激活受体（PPAR）在男睾丸和前列腺的作用
Ewelina Górowska-Wójtowicz,Maja Kudrycka
Ewelina Górowska-Wójtowicz
So far, three types of peroxisome proliferator-activated receptors have been characterized: PPARα, PPARβ (also known as δ) and PPARγ, each characterized by different expression, localization and role. PPAR receptors regulate a number of...