[The role of miRNAs in the pathogenesis, diagnosis, and personalized therapy of glioblastoma multiforme] [0.03%]
微RNA在多形性胶质母细胞瘤发病机制、诊断和个性化治疗中的作用
Anna Bielecka-Wajdman
Anna Bielecka-Wajdman
Glioblastoma multiforme (GBM) is a malignant, hypercellular, and invasive brain tumor characterized by high mortality and recurrence. Their strong heterogeneity, mitotic activity, microvascular proliferation, and foci of necrosis induce the...
Angelika Patelak,Julia Nowak-Niedźwiecka,Beata Machnicka
Angelika Patelak
Ovarian cancer remains one of the most frequently diagnosed and lethal gynaecological malignancies. Standard treatment involves surgical cytoreduction followed by chemotherapy based on platinum compounds and taxanes. Despite initial therape...
Anastazja Woźniczka,Wiktor Pełka,Aleksandra Tarasiuk-Zawadzka et al.
Anastazja Woźniczka et al.
Phytotherapy relies on biologically active plant-derived compounds and preparations. The use of phytotherapeutics in treatment of diabetes consequently increases. Many plant extracts interact with key elements of glucose metabolism, e.g. th...
[Riboregulation in bacteria: From simple switches to complex regulatory networks] [0.03%]
[细菌的核糖调控：从简单的开关到复杂的调节网络]
Paulina Lipska,Julia Konarska,Adrianna Raczkowska et al.
Paulina Lipska et al.
Riboregulation is a key component of bacterial adaptation, as regulatory RNAs enable rapid and precise control of gene expression in response to stress and fluctuating environmental conditions. This control is exerted at the levels of trans...
[Application of analytical protein microarrays in the diagnosis and therapy of lung cancer] [0.03%]
蛋白质微阵列在肺癌诊断和治疗中的应用
Wiktoria Pławecka
Wiktoria Pławecka
Lung cancer is one of the most commonly diagnosed cancers and a leading cause of cancer-related deaths. Analytical protein microarrays are a promising diagnostic tool, particularly for early disease detection. They enable rapid and sensitiv...
[Plant Iridoid Glycosides: Biological Properties and Pharmacological Potential] [0.03%]
[植物いリドイドglycosides：生物特性と薬理学的潜在力]
Ewa Młodzińska-Michta,Natalia Gaik
Ewa Młodzińska-Michta
Iridoid glycosides are a diverse group of plant secondary metabolites with broad biological activity and promising pharmacological potential. This review summarizes their structural diversity, occurrence in plants, biosynthetic pathways, an...
Zuzanna Bieńkowska,Maciej Ołdak,Marta Maleszewska
Zuzanna Bieńkowska
The transcription factor REST (RE1-silencing transcription factor) is a key regulator of neuronal gene expression, playing a role in normal brain development and in the pathogenesis of central nervous system (CNS) tumors. By binding RE1 seq...
[Fungal secondary metabolites as a source of bioactive compounds: a modern approach to their acquisition and analysis] [0.03%]
[真菌次生代谢产物作为生物活性化合物的来源：其获取和分析的现代方法]
Piotr Michałowski,Katarzyna Rynarzewska,Dagmara Nowicka et al.
Piotr Michałowski et al.
Secondary metabolites, which are natural products of fungi, perform key biological functions and have applications in medicine. The production of these compounds is subject to the control of clusters of biosynthetic genes located within the...
[140 years of the model organism Escherichia coli as the "workhorse of molecular biology and biomedicine"] [0.03%]
模式生物体大肠杆菌(Escherichia coli)在分子生物学和生物医药领域服务的140年历程
Beata Sokołowska
Beata Sokołowska
The Escherichia coli bacterium is presented from its discovery in 1885 by the German-Austrian microbiologist and pediatrician Theodor Escherich, to contemporary research using state-of-the-art experimental and bioinformatic techniques, incl...
Jan Barciszewski
Jan Barciszewski