Chronopharmaceutical tablet design for prednisone based on geometry and compression physics independent of excipient influence: a mechanistic approach to controlled release [0.03%]
一种基于几何和压缩物理的泼尼松控释片剂设计方法（与辅料无关）
O Pinarbasli,G P Gurbetoglu,N Sarracoglu et al.
O Pinarbasli et al.
Chronopharmaceutic drug delivery systems are designed to align the release of active substances with the body's biological rhythms, offering significant advantages in diseases with time-dependent symptom patterns. Delayed-release tablets ar...
Risk factors for zolbetuximab-associated nausea and vomiting: a pharmacovigilance analysis using the Japanese Adverse Drug Event Report (JADER) database [0.03%]
基于日本药品不良事件报告(JADER)数据库的佐贝妥昔引发恶心呕吐的风险因素：药物警戒分析
T Nagase,K Shinozaki
T Nagase
Zolbetuximab, a monoclonal antibody against claudin-18.2 (CLDN18.2), improves outcomes in CLDN18.2-positive gastric cancer, but gastrointestinal adverse events-especially nausea and vomiting-are frequently reported. Using PMDA-JADER (April ...
Phytochemical characterisation of pharmaceutical extracts from Equisetum arvense L. by HPLC-DAD-MSn and GC-MS [0.03%]
高效液相色谱-四级杆/离子阱质谱联用法研究药用鼠尾草提取物的植物化学成分.characterization of phytochemicals from pharmaceutical extracts of Equisetum arvense L. by hplc-dad-msn and gc-ms
K Nosrati Gazafroudi,L K Mailänder,R Daniels et al.
K Nosrati Gazafroudi et al.
Equisetum arvense L., commonly known as horsetail, is the most prominent Equisetum species and a widely used medicinal plant in traditional and herbal medicine. This study presents a comprehensive phytochemical characterisation of various p...
Off-label prescribing in the pediatric population: perceptions and practices of community pharmacists in Kosovo - a cross-sectional survey [0.03%]
科索沃社区药剂师对儿科患者超说明书用药的认知与实践——横断面调查研究
A Koshi,R Koliqi,P Breznica Selmani et al.
A Koshi et al.
Off-label drug prescribing in pediatric populations is a common practice worldwide due to the limited availability of approved formulations and clinical data for children. While often necessary, it raises concerns regarding safety, efficacy...
Development and validation of a qNMR method for the simultaneous quantification of creatine and taurine in sports supplements [0.03%]
用于运动营养品中肌酸和牛磺酸的同时定量的qNMR方法的开发与验证
R Van Der Merwe,D P Otto,W Liebenberg et al.
R Van Der Merwe et al.
Creatine and taurine are frequently found together in sports supplements due to their performance-enhancing and metabolic benefits. However, discrepancies between label claims and actual content have raised concerns about product quality, r...
Nephrotoxicity and associated risk factors in patients treated with pemetrexed [0.03%]
培美曲塞治疗患者的肾毒性及影响因素分析
Y Yamamoto,N Orito,N Watanabe et al.
Y Yamamoto et al.
Purpose: Pemetrexed causes renal impairment. However, few studies have investigated the risk factors associated with pemetrexed-induced renal impairment. This study aimed to investigate the incidence of nephrotoxicity in patients receiving ...
Persisting infections under IgG substitution: Need for further improvement [0.03%]
IgG替代疗法下感染的持续存在：进一步改进的要求
A Wartenberg-Demand,C Staiger,K Warnatz
A Wartenberg-Demand
Since many years, immunoglobulin G (IgG) substitution has been used to treat patients with primary immunodeficiencies (PID) to reduce the number of infections and the burden of disease. Nevertheless, many patients continue to suffer from pe...
Comparison of vancomycin and teicoplanin for febrile neutropenia following hematopoietic stem cell transplantation [0.03%]
造血干细胞移植后发热性中性粒细胞减少的万古霉素与替考拉宁的对比研究
T Nakashima,O Kobayashi,K Okinaka et al.
T Nakashima et al.
Febrile neutropenia is a common complication of hematopoietic stem cell transplantation. Although anti-MRSA agents such as vancomycin and teicoplanin are widely used for treatment, their clinical efficacy and safety during the early post-tr...
Comparative Study
Die Pharmazie. 2025 Dec 1;80(11):132-136. DOI:10.1691/ph.2025.5609 2025
A multicenter randomized controlled trial in patients with type 2 diabetes mellitus to evaluate an "advanced pharmaceutical care" intervention for the prevention of adverse effects and drug-related problems in a follow-up home visit (BayPharmCareDiabetesTrail) [0.03%]
2型糖尿病患者接受“高级药品护理”干预的效果：一项多中心随机对照试验（BayPharmCare糖尿病试验）
J Gabsteiger,A Paul,J Landwehr et al.
J Gabsteiger et al.
Background and aim: Studies provide strong evidence for antidiabetic efficacy of certain drugs but adverse events (AEs) and drug-related problems (DRPs) limit their effectiveness. Investigations: Patients with type-2 diabetes mellitus of co...
Randomized Controlled Trial
Die Pharmazie. 2025 Dec 1;80(11):149-155. DOI:10.1691/ph.2025.5623 2025
Human-Resource-Development for the future provision of Clinical Pharmaceutical Services [0.03%]
未来临床药学服务人才发展的培养教育
L Riedel,A Lange -Böhmer,T Bertsche
L Riedel
Background and aim: To implement Clinical Pharmaceutical Services (CPS) in routine hospital care with limited resources, their use should be prioritized. We present an objectifiable approach to planning development particularly for pharmace...