F J RYAN,J LEDERBERG
F J RYAN
M E SANDERS,P R BURKHOLDER
M E SANDERS
F Stephen Dobson
F Stephen Dobson
Yingying Guo,Peng Lu,Erin Farrell et al.
Yingying Guo et al.
Combining the experimental efficiency of a murine hepatic in vitro drug biotransformation system with in silico genetic analysis produces a model system that can rapidly analyze interindividual differences in drug metabolism. This model sys...
Regulatory evolution in proteins by turnover and lineage-specific changes of cyclin-dependent kinase consensus sites [0.03%]
周期素依赖蛋白激酶共识位点的更替及谱系特异性变化驱动蛋白质中的调控进化
Alan M Moses,Muluye E Liku,Joachim J Li et al.
Alan M Moses et al.
Evolutionary change in gene regulation is a key mechanism underlying the genetic component of organismal diversity. Here, we study evolution of regulation at the posttranslational level by examining the evolution of cyclin-dependent kinase ...
Ingemar André,Philip Bradley,Chu Wang et al.
Ingemar André et al.
Biological supramolecular systems are commonly built up by the self-assembly of identical protein subunits to produce symmetrical oligomers with cyclical, icosahedral, or helical symmetry that play roles in processes ranging from allosteric...