E E Kopantseva,A V Belyavsky
E E Kopantseva
Skeletal myogenesis has been extensively studied at both morphological and molecular levels. This review considers the main stages of embryonic skeletal myogenesis and myogenic factors that trigger their initiation, focusing on specific pro...
[Downregulation of Human Adenovirus DNA Polymerase Gene by Modified siRNAs] [0.03%]
经修饰的siRNA下调人腺病毒DNA聚合酶基因
N A Nikitenko,T Speiseder,E L Chernolovskaya et al.
N A Nikitenko et al.
Human adenoviruses, in particular D8, D19, and D37, cause ocular infections. Currently, there is no available causally directed treatment, which efficiently counteracts adenoviral infectious diseases. In our previous work, we showed that ge...
[Changes in the Expression of Dopaminergic Genes in Brain Structures of Male Mice Exposed to Chronic Social Defeat Stress: An RNA-seq Study] [0.03%]
慢性社会挫败应激雄性小鼠脑内多巴胺能基因表达变化的转录组研究
I L Kovalenko,D A Smagin,A G Galyamina et al.
I L Kovalenko et al.
Whole-transcriptome analysis (RNA-seq) has been used to analyze changes in the expression of dopaminergic genes that encode proteins involved in the synthesis, inactivation, and neurotransmission of dopamine in the striatum, ventral tegment...
[Alpha-1 Antitrypsin Affects U0126-Induced Cytotoxicity in Colon Cancer Cell Line (HCT116)] [0.03%]
[α-1抗胰蛋白酶影响U0126诱导的结肠癌细胞系（HCT116）毒性]
M Ljujic,S Mijatovic,M Z Bulatovic et al.
M Ljujic et al.
Alpha-1-antitrypsin (AAT), an acute phase protein, is the principal circulatory anti-protease. This multifunctional protein is encoded by the SERPINA1 gene. Although AAT was recognised as a potential tumour marker, its role in cancer biolog...
[Hypothetical SNP Markers That Significantly Affect the Affinity of the TATA-Binding Protein to VEGFA, ERBB2, IGF1R, FLT1, KDR, and MET Oncogene Promoters as Chemotherapy Targets] [0.03%]
[假设的SNP标记，这些标记显著影响TATA结合蛋白与VEGFA、ERBB2、IGF1R、FLT1、KDR和MET致癌基因启动子之间亲和力的化疗靶点]
I I Turnaev,D A Rasskazov,O V Arkova et al.
I I Turnaev et al.
The following hypothesis has been proposed: IF an SNP can significantly increase the expression of an oncogene by increasing the affinity of the TATA-binding protein (TBP) to its promoter, THEN this SNP can also reduce the apparent bioactiv...
[GH10 Family of Glycoside Hydrolases: Structure and Evolutionary Connections] [0.03%]
糖苷水解酶GH10家族：结构与进化关系
D G Naumoff
D G Naumoff
Evolutionary connections were analyzed for endo-β-xylanases, which possess the GH10 family catalytic domains. A homology search yielded thrice as many proteins as are available from the Carbohydrate-Active Enzymes (CAZy) database. Lateral ...
[Identification of the Disease-Associated Genes in Periodontitis Using the Co-expression Network] [0.03%]
基于共表达网络的牙周病致病基因识别研究
G P Sun,T Jiang,P F Xie et al.
G P Sun et al.
The aim of this study was to investigate the disease-associated genes in periodontitis. In the present experiments, the topological analysis of the differential co-expression network was proposed. Using the GSE16134 dataset downloaded from ...
[The Role of Calcium in the Conformational Changes of the Recombinant S100A8/S100A9] [0.03%]
钙在重组S100A8/S100A9构象变化中作用的研究
N Gheibi,H Asghari,K G Chegini et al.
N Gheibi et al.
Calprotectin is a member of the EF-hand proteins, composed of two subunits, S100A8 (MRP8) and S100A9 (MRP14). These proteins are involved in important processes including cell signaling, regulation of inflammatory responses, cell cycle cont...
[Increase in GP IIb-IIIa and P2Y12 Receptors in Activated Platelets as the Possible Indicator of de novo Protein Synthesis] [0.03%]
活化血小板GP IIb-IIIa和P2Y12受体增加可能为de novo蛋白质合成所致
O V Sirotkina,A B Laskovets,P A Andoskin et al.
O V Sirotkina et al.
Although platelets lack nuclei, they are capable of de novo protein synthesis. We speculate that key platelet receptors are involved in the regulation of this process, and the changes in their number indicate the de novo protein synthesis i...