[Influence of chronic alcohol treatment on the expression of the Bdnf, Bax, Bcl-xL, and CASP3 genes in the mouse brain: Role of the C1473G polymorphism in the gene encoding tryptophan hydroxylase 2] [0.03%]
慢性酒精处理对小鼠脑源性神经营养因子及促凋亡和抗凋亡基因bax、Bcl-xL、CASP3表达的影响及二羟色氨酸羟化酶2基因1473位点多态性的作用机制研究
D V Bazovkina,A S Tsybko,E A Filimonova et al.
D V Bazovkina et al.
Tryptophan hydroxylase 2 (Tph-2) is the key enzyme in serotonin biosynthesis. Serotonin is one of the main neurotransmitters involved in the regulation of various physiological functions and behavior patterns. The influence of chronic ethan...
[Effect of endonuclease G depletion on plasmid DNA uptake and levels of homologous recombination in hela cells] [0.03%]
端脱氧核糖核酸内切酶G敲低对宫颈癌细胞hek293和hei Cells质粒DNA摄取及同源重组水平的影响
V Misic,M El-Mogy,S Geng et al.
V Misic et al.
Endonuclease G (EndoG) is a mitochondrial apoptosis regulator that also has roles outside of programmed cell death. It has been implicated as a defence DNase involved in the degradation of exogenous DNA after transfection of mammalian cells...
[Protective effects of S-adenosylmethionine against CCl4 - and ethanol-induced experimental hepatic fibrosis] [0.03%]
[S-腺苷甲硫氨酸对四氯化碳和乙醇所致实验性肝纤维化的保护作用]
F Zhang,J-X Gu,X-P Zou et al.
F Zhang et al.
In this study the effects of S-adenosylmethionine (SAM) on experimental hepatic fibrotic rats induced by carbon tetrachloride (CCl(4)) and ethanol and the relevant potential mechanisms were explored. Hepatic fibrotic rat models were establi...
[Evaluation of miR-122 level in the plasma of chronically HCV infected patients] [0.03%]
慢性丙型肝炎患者血浆miR-122水平检测及其评价
M Gholami,M Ravanshad,S-M Alavian et al.
M Gholami et al.
MicroRNAs (miRNAs) are small non-coding RNA molecules, which have an important function in regulating RNA stability and gene expression. They also can circulate in a cell-free form in the blood thatmakes them potential disease markers. The ...
[PCR-based evaluation of sequence specificity of DNA fragmentation by ultrasound] [0.03%]
基于PCR的超声波特异性断裂DNA研究
R R Garafutdinov,A A Galimova,A R Sakhabutdinova et al.
R R Garafutdinov et al.
Ultrasonic fragmentation, which is a simple and convenient method for the mechanical degradation of DNA, is widely used in modern genome studies as one of the sample preparation steps. It has been recently found that the DNA breaks occur mo...
[Influence of dexamethasone on the expression of immediate early genes c-fos and c-jun in different regions of the neonatal brain] [0.03%]
地塞米松对新生鼠脑不同区室即刻早期基因c-fos和c-jun表达的影响
E V Sukhareva,N N Dygalo,T S Kalinina
E V Sukhareva
The ratio of the expression levels of the immediate early genes c-jun and c-fos that encode components of the AP-1 transcription complex determines the direction of changes in the expression of genes controlled by the complex, including cha...
[Abnormal expression of genes that regulate retinoid metabolism and signaling in non-small-cell lung cancer] [0.03%]
非小细胞肺癌中调控视黄醇代谢和信号的基因异常表达
E S Kuznetsova,O L Zinovieva,N Yu Oparina et al.
E S Kuznetsova et al.
Retinoids are signaling molecules that control a wide variety of cellular processes and possess antitumor activity. This work presents a comprehensive description of changes in the expression of 23 genes that regulate retinoid metabolism an...
[Gene Polymorphism of the c-fms, ITGB3,CCR2, and DBH genes in the populations of old believers of the Tyumen oblast and Russian residents of Novosibirsk] [0.03%]
俄罗斯托木斯克老信徒和新西伯利亚居民的c-fms、ITGB3、CCR2和DBH基因多态性研究
M A Gubina,V N Babenko,D E Ivanoshchuk et al.
M A Gubina et al.
Old Believers of the Tyumen oblast have been studied compared with a control sample of Russian residents of the city of Novosibirsk. The former are a unique subpopulation, which has been relatively isolated from the rest of Russians in cent...
K V Sivak,A V Vasin,V V Egorov et al.
K V Sivak et al.
Sepsis is a generalized infection accompanied by response of the body that manifests in a clinical and laboratory syndrome, namely, in the systemic inflammatory response syndrome (SIRS) from the organism to the infection. Although sepsis is...
[Role of the ABC transporters A1 and G1, key reverse cholesterol transport proteins, in atherosclerosis] [0.03%]
ABC转运体A1和G1在动脉粥样硬化中的作用及其作为关键逆向胆固醇运输蛋白的特性
E P Demina,V V Miroshnikova,A L Schwarzman
E P Demina
Atherosclerosis is one of the most common causes of death worldwide. Epidemiology studies firmly established an inverse relationship between atherogenesis and distorted lipid metabolism, in particular, higher levels of total cholesterol, an...