[Expression of Long Noncoding RNAs and Protein-Coding Genes Involved in Oxidative Stress and Cell Senescence in Patients with Chronic Obstructive Pulmonary Disease] [0.03%]
慢性阻塞性肺疾病患者氧化应激和细胞衰老相关长链非编码RNA及蛋白编码基因的表达
V A Markelov,G F Korytina,Y G Aznabaeva et al.
V A Markelov et al.
Chronic obstructive pulmonary disease (COPD) is a multifactorial heterogeneous chronic inflammatory respiratory disease. The molecular pathogenesis of COPD may include dysregulation of the stress responses that are associated with cell sene...
[Redox Status and Protein Glutathionylation in Binase-Treated HPV16-Positive SiHa Carcinoma Cells] [0.03%]
Binase处理的HPV16阳性SiHa癌细胞的抗氧化状态和蛋白质谷胱甘肽化修饰研究
A I Nadyrova,I Y Petrushanko,V A Mitkevich et al.
A I Nadyrova et al.
Human papillomavirus type 16 (HPV16) belongs to viruses of the high-risk type and is associated by overexpression of E6 and E7 oncoproteins, which determine the oncogenic properties of the virus, such as immortalization and malignant transf...
[Structure and Function of the Transglutaminase Cluster in the Basal Metazoan Halisarca dujardinii (Sponge)] [0.03%]
基底后生动物Halisarca dujardinii（海绵）的转谷氨酰胺酶簇的结构与功能
A D Finoshin,O I Kravchuk,K V Mikhailov et al.
A D Finoshin et al.
Transglutaminases are enzymes that carry out post-translational modifications of proteins and participate in the regulation of their activities. Here, we show for the first time that the transglutaminase genes in the basal metazoan, the sea...
[Inactivation of Type 3 Fimbriae Increases Adhesion of Klebsiella oxytoca to Lung Epithelial Cells] [0.03%]
III型菌毛的失活增加了肺炎克雷伯氏菌对肺上皮细胞的粘附力
A G Giliazeva,A M Mardanova
A G Giliazeva
Klebsiella oxytoca is a causative agent of various community-acquired and nosocomial infections, including urinary tract infections, nosocomial pneumonia, antibiotic-associated diarrhea, etc. However, the virulence factors of the species ar...
[GRIP1 is Involved in the Interaction of Vimentin Filaments with Focal Adhesions in Endothelial Cells] [0.03%]
[GRIP1参与内皮细胞中波形蛋白丝与 focal adhesions 的相互作用]
注：由于 "focal adhesions" 在生物学领域通常指的是细胞骨架和细胞外基质之间的连接结构，且在中文语境下没有特别约定俗成的翻译，因此这里保持了英文原词。如果需要完全翻译为中文，则可以将其译为“焦点黏着”，但请注意这可能会影响专业读者的理解。
更准确的翻译可能是：[GRIP1参与内皮细胞中波形蛋白丝与粘着斑的相互作用]
F K Gyoeva
F K Gyoeva
Vimentin intermediate filaments are dynamic structures that are able to move in cytoplasm owing to activity of the motor proteins, kinesin-1 and cytoplasmic dynein. How exactly motors interact with vimentin filaments remains unclear. In thi...
[Spatial Organization of Chromatin of the KLF5 Gene Promoter Region in Pancreatic Ductal Adenocarcinoma Cells] [0.03%]
胰腺导管腺癌细胞中KLF5基因启动子区域染色质的空间组织结构
M V Zinovyeva,L G Nikolaev
M V Zinovyeva
Pancreatic Ductal AdenoCarcinoma (PDAC) is characterized by a poor prognosis and is poorly amenable to modern therapies. A range of cell cultures reflecting different degrees of tumor differentiation and malignancy can serve as a model of P...
[Search for Transposable Element Insertions and Chromosomal Rearrangements That Change Gene Expression in D. melanogaster Strains with Impaired Transposition Control of gypsy Retrotransposon] [0.03%]
改变基因表达的转座元件插入和染色体畸变在D. melanogaster菌株中由于gypsy长末端重复序列转座子转座调控失灵引起
I V Kukushkina,A R Lavrenov,P A Milyaeva et al.
I V Kukushkina et al.
Transposable elements (TEs) increase the frequency of spontaneous mutations in the genome and are capable of altering the gene structure and expression. TE activities and genomic positions are therefore important to study. A combination of ...
[Geroprotective Properties of the ATM Inhibitor KU-60019 in Three Drosophila Species Differing in Lifespan] [0.03%]
ATM抑制剂KU-60019在三种寿命不同的果蝇中具有促长寿的特性
L A Koval&#x;,N V Zemskaya,N P Pakshina et al.
L A Koval&#x; et al.
Serine/threonine protein kinase ATM (ataxia-telangiectasia mutated) performs a number of aging-related functions in the cell. In addition to regulating the cell response to DNA damage, ATM phosphorylates vacuolar ATPase and thus leads to ly...
G A Shilovsky
G A Shilovsky
Numerous regulatory cascades link the cell response to oxidative stress and the mechanisms that maintain homeostasis and cell viability. The review summarizes the molecular mechanisms of interaction of the autophagy protein p62 with cell de...
[Methylation of Selected CpG-Sites of the Gene CSF1 as a Factor in Regulation of Its Expression and a Marker of Human Biological Aging] [0.03%]
基因CSF1的选定CpG位点的甲基化作为其表达调控因素和人类生物衰老标志物
A D Sergeeva,A D Perenkov,M V Vedunova
A D Sergeeva
Age-associated transformation of methylation patterns is considered to be an important predictor of human biological age. Changes in the level of CpG-dinucleotide methylation contribute to a shift in the function of a number of genes, inclu...