Endoscopic skull base surgery: principles of endonasal oncological surgery [0.03%]
内镜颅底外科手术：内镜鼻腔肿瘤切除术原则
Carl H Snyderman,Ricardo L Carrau,Amin B Kassam et al.
Carl H Snyderman et al.
Endoscopic endonasal surgery can be applied to the management of benign and malignant sinonasal neoplasms with good results. For tumors that involve the skull base, an endoscopic "craniofacial resection" can be performed with en bloc excisi...
Staging of head and neck cancers: is it time to change the balance between the ideal and the practical? [0.03%]
理想与实践之争——头颈部肿瘤分期评估再思考
Snehal G Patel,William M Lydiatt
Snehal G Patel
The TNM system is a widely accepted prognostic system worldwide. Limitations in prognostic accuracy are recognized but have remained for fear the remedy would unnecessarily complicate the system. Understanding of the genetic and molecular m...
Richard J Wong
Richard J Wong
18-FDG-PET has utility for the identification of the unknown primary head and neck squamous carcinoma, distant metastases or second primary carcinomas, and recurrent HNSCC in the post-treatment setting. PET has a high negative predictive va...
Gaurang V Shah,Jeffery R Wesolowski,Sameer A Ansari et al.
Gaurang V Shah et al.
Computerized tomography (CT) and magnetic resonance imaging (MRI), positron emission tomography (PET) and the hybrid modality of PET/CT are sensitive and reliable tools for detection and staging of head and neck cancers. This article descri...
Steven S Chang,Joseph Califano
Steven S Chang
As our understanding of HNSCC increases so has biomarker development. HPV16 integration is a significant marker of favorable prognosis and response to therapy for HNSCC. EGFR-amplification and overexpression is a poor-prognostic indicator. ...
Bhuvanesh Singh
Bhuvanesh Singh
Head and neck cancers represent a progressive genetic malady, with genetic aberrations accumulating in response to carcinogen exposure. Although individual genomic aberrations develop at specific time points in the progression axis, the pre...
Patrick J Gullane
Patrick J Gullane
Ashok R Shaha
Ashok R Shaha
Ashok R Shaha
Ashok R Shaha
Management of head and neck cancer truly represents the need for a multimodality approach. This manuscript discusses the history of head and neck surgery, head and neck fellowships and the current trends in the practice of head and neck sur...