Arrays of Segmented, Tapered Light Guides for Use with Large, Planar Scintillation Detectors [0.03%]
用于大型平面闪烁探测器的分段渐变光导列阵
Raymond R Raylman,Keith Vaigneur,Alexander V Stolin et al.
Raymond R Raylman et al.
Metabolic imaging techniques can potentially improve detection and diagnosis of cancer in women with radiodense and/or fibrocystic breasts. Our group has previously developed a high-resolution positron emission tomography imaging and biopsy...
George A Kastis,Lars R Furenlid,Donald W Wilson et al.
George A Kastis et al.
We have developed a dual-modality CT/SPECT imaging system for small-animal imaging applications. The X-ray system comprises a commercially available micro-focus X-ray tube and a CCD-based X-ray camera. X-ray transmission measurements are pe...
A Pullia,H W Kraner,D P Siddons et al.
A Pullia et al.
A multichannel silicon pad detector for EXAFS (Extended X-ray Absorption Fine Structure) applications has been designed and built. The X-ray spectroscopic measurements demonstrate that an adequate energy resolution of 230 eV FWHM (correspon...
Impact of the Fano Factor on Position and Energy Estimation in Scintillation Detectors [0.03%]
方差因子对闪烁探测器中位置和能量估计的影响
Vaibhav Bora,Harrison H Barrett,Abhinav K Jha et al.
Vaibhav Bora et al.
The Fano factor for an integer-valued random variable is defined as the ratio of its variance to its mean. Light from various scintillation crystals have been reported to have Fano factors from sub-Poisson (Fano factor < 1) to super-Poisson...
A DOI Detector With Crystal Scatter Identification Capability for High Sensitivity and High Spatial Resolution PET Imaging [0.03%]
一种具有晶体散射识别能力的DOI探测器用于高灵敏度和高空间分辨率PET成像
Z Gu,D L Prout,R W Silverman et al.
Z Gu et al.
A new phoswich detector is being developed at the Crump Institute, aiming to provide improvements in sensitivity, and spatial resolution for PET. The detector configuration is comprised of two layers of pixelated scintillator crystal arrays...
First-Pass Angiography in Mice Using FDG-PET: A Simple Method of Deriving the Cardiovascular Transit Time Without the Need of Region-of-Interest Drawing [0.03%]
使用FDG-PET进行小鼠首次通透血管造影的简便方法：无需绘制感兴趣区域即可获得心血管转运时间
Hsiao-Ming Wu,Michael C Kreissl,Heinrich R Schelbert et al.
Hsiao-Ming Wu et al.
In this study, we developed a simple and robust semi-automatic method to measure the right ventricle to left ventricle (RV-to-LV) transit time (TT) in mice using 2-[18F]fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET). The ...
A System Calibration and Fast Iterative Reconstruction Method for Next-Generation SPECT Imagers [0.03%]
下一代SPECT成像仪的系统校准与快速迭代重建方法
Brian W Miller,Roel Van Holen,Harrison H Barrett et al.
Brian W Miller et al.
Recently, high-resolution gamma cameras have been developed with detectors containing > 105-106 elements. Single-photon emission computed tomography (SPECT) imagers based on these detectors usually also have a large number of voxel bins and...
Abhinav K Jha,Herman T van Dam,Matthew A Kupinski et al.
Abhinav K Jha et al.
The response of a Silicon Photomultiplier (SiPM) to optical signals is affected by many factors including photon-detection efficiency, recovery time, gain, optical crosstalk, afterpulsing, dark count, and detector dead time. Many of these p...
Combining MRI with PET for partial volume correction improves image-derived input functions in mice [0.03%]
结合MRI和PET进行部分容积校正可改善小鼠的图像输入函数
Eleanor Evans,Guido Buonincontri,David Izquierdo et al.
Eleanor Evans et al.
Accurate kinetic modelling using dynamic PET requires knowledge of the tracer concentration in plasma, known as the arterial input function (AIF). AIFs are usually determined by invasive blood sampling, but this is prohibitive in murine stu...
Fisher Information Analysis of Depth-of-Interaction Estimation in Double-Sided Strip Detectors [0.03%]
双面 strip 探测器深度交互估计的 Fisher 信息分析
Esen Salçin,Harrison H Barrett,H Bradford Barber et al.
Esen Salçin et al.
In very-high-spatial-resolution gamma-ray imaging applications, such as preclinical PET and SPECT, estimation of 3D interaction location inside the detector crystal can be used to minimize parallax error in the imaging system. In this work,...