Ryan M Layer,Aaron R Quinlan
Ryan M Layer
The comparison of sets of genome intervals (e.g., genes, repeats, ChIP-seq peaks) is essential to genome research, especially as modern sequencing technologies enable ever larger and more complex experiments. Relationships between genomic f...
Iain M Johnstone,Debashis Paul
Iain M Johnstone
When the data are high dimensional, widely used multivariate statistical methods such as principal component analysis can behave in unexpected ways. In settings where the dimension of the observations is comparable to the sample size, upwar...
DANUBE: Data-driven meta-ANalysis using UnBiased Empirical distributions-applied to biological pathway analysis [0.03%]
基于无偏经验分布的元分析的数据驱动方法及其在生物学通路分析中的应用 DANUBE算法
Tin Nguyen,Cristina Mitrea,Rebecca Tagett et al.
Tin Nguyen et al.
Identifying the pathways and mechanisms that are significantly impacted in a given phenotype is challenging. Issues include patient heterogeneity and noise. Many experiments do not have a large enough sample size to achieve the statistical ...
Diane J Cook,Glen Duncan,Gina Sprint et al.
Diane J Cook et al.
Smart cities use information and communication technologies (ICT) to scale services include utilities and transportation to a growing population. In this article we discuss how smart city ICT can also improve healthcare effectiveness and lo...
Abram Magner,Daisuke Kihara,Wojciech Szpankowski
Abram Magner
We rigorously study a channel that maps sequences from a finite alphabet to self-avoiding walks in the two-dimensional grid, inspired by a model of protein folding from statistical physics and studied empirically by biophysicists. This chan...
Hamid Gharavi,Bin Hu
Hamid Gharavi
This paper focuses primarily on leveraging synchronized current/voltage amplitudes and phase angle measurements to foster new categories of applications, such as improving the effectiveness of grid protection and minimizing outage duration ...
Advances in two photon scanning and scanless microscopy technologies for functional neural circuit imaging [0.03%]
用于功能神经环路成像的双光子扫描和无扫描显微镜技术进展
Simon R Schultz,Caroline S Copeland,Amanda J Foust et al.
Simon R Schultz et al.
Recent years have seen substantial developments in technology for imaging neural circuits, raising the prospect of large scale imaging studies of neural populations involved in information processing, with the potential to lead to step chan...
Fusing multiple neuroimaging modalities to assess group differences in perception-action coupling [0.03%]
融合多种神经影像模性评估感知-行动耦合的群体差异
Jordan Muraskin,Jason Sherwin,Gregory Lieberman et al.
Jordan Muraskin et al.
In the last few decades, non-invasive neuroimaging has revealed macro-scale brain dynamics that underlie perception, cognition and action. Advances in non-invasive neuroimaging target two capabilities; 1) increased spatial and temporal reso...
Analysis of Thickness and Quality factor of a Double Paddle Oscillator at Room Temperature [0.03%]
室温双桨摆厚径比及品质因子分析
Hamza Shakeel,Thomas H Metcalf,J M Pomeroy
Hamza Shakeel
In this paper, we evaluate the quality (Q) factor and the resonance frequency of a double paddle oscillator (DPO) with different thickness using analytical, computational and experimental methods. The study is carried out for the 2nd anti-s...
Stefan Canzar,Steven L Salzberg
Stefan Canzar
Ultra-high-throughput next-generation sequencing (NGS) technology allows us to determine the sequence of nucleotides of many millions of DNA molecules in parallel. Accompanied by a dramatic reduction in cost since its introduction in 2004, ...