[Pharmacological characteristics and clinical outcomes of Rimegepant (Nurtec® ODT), an oral CGRP receptor antagonist for the acute treatment and prevention of migraine] [0.03%]
瑞美吉泮(Nurtec® ODT)的药理特性及其用于急性治疗和预防偏头痛的临床疗效
Tomofumi Ishikawa,Saori Morota,Beini Shi et al.
Tomofumi Ishikawa et al.
Migraine is a highly prevalent neurological disorder and is associated with substantial mental, social, and disease burden. Current migraine management comprises acute and preventive treatments; however, conventional acute and preventive me...
[Pharmacological properties and clinical trial results of datopotamab deruxtecan (Dato-DXd, Datroway®)] [0.03%]
德达博利单抗杜克替康(Dato-DXd,代罗韦)的药学属性及临床试验结果综述
Takahiro Iijima,Daisuke Okajima
Takahiro Iijima
Antibody-drug conjugate (ADC) is a next-generation antibody therapeutics designed to deliver drugs selectively and efficiently to cancer cells, offering high efficacy and reduced side effects. Daiichi Sankyo has established a novel DXd-ADC ...
[Oxytocin regulates social familiarity-dependent mate choice in medaka] [0.03%]
[催产素调节鳉鱼基于社会熟悉度的配偶选择]
Saori Yokoi
Saori Yokoi
Some social animals have evolved the ability to distinguish between familiar and unfamiliar individuals and to flexibly modify their behavior according to social context. Disruption of this system has been implicated in neurodevelopmental d...
Mikuru Kudara,Haruka Suzuki,Yuji Ikegaya et al.
Mikuru Kudara et al.
Our understanding of the neural mechanisms underlying social behavior has been advanced by research using mice and rats. Specifically, the dorsal hippocampal CA2 area, ventral hippocampal CA1 area, and nucleus accumbens have been identified...
Nobuyoshi Matsumoto,Saori Yokoi
Nobuyoshi Matsumoto
[Light stress-induced damage to intracellular membrane organelles and its preventive strategies] [0.03%]
[轻度胁迫引起的胞内膜相结构损伤及其防护机制]
Wataru Otsu
Wataru Otsu
Photoreceptor cells in the retina are highly specialized sensory cells that function as light receptors. During the conversion of light into neural signals, photoreceptors are constantly exposed to oxidative stress. Although environmental s...
Junko Nio-Kobayashi
Junko Nio-Kobayashi
Although the main component of cell membrane is phospholipids, there are regions that are rich in glycosphingolipids and cholesterol, called membrane microdomains. Membrane microdomains are densely populated with receptors and intra/extrace...
[Mechanistic insights into maintenance and disruption of membrane phosphatidylserine asymmetry in human erythrocytes: a survival strategy during their lifespan] [0.03%]
[人红细胞膜磷脂酰丝氨酸不对称分布的维持和破坏的机制探讨——其生命周期中的生存策略]
Momoko Seki,Nobuto Arashiki,Junichi Hoshino et al.
Momoko Seki et al.
Human erythrocytes retain phosphatidylserine (PS) only in the inner leaflet of plasma membranes during their 120-day lifespan to enforce membrane strengthen through associations with cytoskeletal proteins. Meanwhile, PS is exposed to the ou...