Delivery-Associated Changes in the Levels of Inflammatory Molecules in Newborns [0.03%]
新生儿递送相关的炎症分子的变化水平
Marek Mojžíšek,Michaela Šibíková,Martin Pánek et al.
Marek Mojžíšek et al.
Inflammation is considered a fundamental process accompanying physiological human birth, also playing a role in perinatal pathologies. The goal of the study was to assess the concentrations of inflammatory molecules with respect to the mode...
Chondrosarcoma with Target-Like Chondrocytes: Update on Molecular Profiling and Specific Morphological Features [0.03%]
靶样软骨细胞型软骨肉瘤的分子特征和组织学特点更新
C Povýšil,J Hojný,M Kaňa
C Povýšil
The original article was published in Folia Biologica (Praha) Volume 68, No. 3 (2022), 112-124.
Published Erratum
Folia biologica. 2022;68(5-6):112-124. DOI: 2022
No Inhibitory Effect of Heparinized Blood on Real-Time PCR Analysis of Thrombophilic Mutations [0.03%]
肝素化血液标本对凝血分子生物学检测结果无影响
M Beránek,J Hegerová,M Michajlíková et al.
M Beránek et al.
We compared the efficiency of real-time PCR analysis of FII (c.*97G>A, G20210A) and FV Leiden (c.1601G>A) thrombophilic mutations in the samples obtained from venous blood treated with various anti coagulant agents (EDTA, heparin, and sodiu...
Mechanistic Study of Macranthoside B Effects on Apoptotic Cell Death in Human Cervical Adenocarcinoma Cells [0.03%]
黄花夹竹桃素B诱导人宫颈腺癌细胞凋亡的机制研究
Y Li,M Li,K Ahmed et al.
Y Li et al.
Macranthoside B (MB) is a triterpenoid saponin extracted from Lonicera macranthoides, a traditional Chinese medicine. In the current study, we investigated the anticancer potential of MB in various cancer cells and elucidated its underlying...
Up-regulation of MiR-146b-5p Inhibits Fibrotic Lung Pericytes via Inactivation of the Notch1/PDGFRβ/ROCK1 Pathway [0.03%]
miR-146b-5p上调通过抑制Notch1/PDGFRβ/ROCK1信号通路来减少纤维化肺球管肌成纤维细胞的增殖和迁移
W Shuai,Q Chen,X Zhou
W Shuai
Lung fibrosis is a serious human pathology. MiR-146b-5p is down-regulated in idiopathic pulmonary fibrosis, and the Notch1/PDGFRβ/ROCK1 pathway is activated. However, the relation between miR-146b-5p and the Notch1/PDGFRβ/ROCK1 pathway in...
Genetics of T2DM and Its Chronic Complications: Are We Any Closer to the Individual Prediction of Genetic Risk? [0.03%]
2型糖尿病及其慢性并发症的遗传学：我们更接近于个体预测基因风险了吗？
D Galuška,L Dlouhá,J A Hubáček et al.
D Galuška et al.
Type 2 diabetes mellitus (T2DM) is a complex disease that has risen in global prevalence over recent decades, resulting in concomitant and enormous socio-economic impacts. In addition to the well-documented risk factors of obesity, poor die...
Review
Folia biologica. 2022;68(5-6):159-179. DOI: 2022
Circulating Cell-Free DNA Extraction from Liquid Biopsy for Cancer Research [0.03%]
循环肿瘤DNA液体活检技术在癌症研究中的应用
L Pfeiferova,M Safarikova,J Ulrych et al.
L Pfeiferova et al.
As the number of cancer patients globally increases, a need for reliable biomarkers including circulating tumour DNA from liquid biopsy for diagnosis, prognosis and monitoring of the disease is rising. Currently, mainly tissue samples from ...
Ultra-Small Gold Nanoparticles with Mild Immunomodulatory Activity as a Potential Tool for Bio-Applications [0.03%]
具有轻度免疫调节作用的超小型金纳米颗粒作为生物应用的潜在工具
T Bělinová,P Javorová,H Y Nguyenová et al.
T Bělinová et al.
Recently, more and more efforts are directed towards developing new imaging and drug-delivery options based on various nanoparticles, exploiting their unique properties. Here, ultra-small gold nanoparticles functionalized with widely used p...
Limonitum Ameliorates Castor Oil-Induced Diarrhoea in Mice by Modulating Gut Microbiota [0.03%]
番泻油诱导的小鼠腹泻模型中地菍通过调控肠道菌群改善腹泻症状
Y L Ma,B F Yan,J Liu et al.
Y L Ma et al.
Diarrhoea is a common clinical condition; its pathogenesis is strongly associated with gut microbiota dysbiosis. Limonitum is a well-known traditional Chinese medicine that exerts appreciable benefits regarding the amelioration of diarrhoea...
Antigen Presentation and Proteome Study of Exosomes Secreted by Co-Culture of Macrophages and Talaromyces marneffei [0.03%]
宏噬细胞与马尼菲青霉共培养分泌的外泌体抗原呈递及蛋白质组学研究
Z Xie,L L Li,G J Wei et al.
Z Xie et al.
It is known that intracellular pathogens interact and react with the cellular immune system through exosomes produced by macrophages. This study aimed to determine whether co-culture of macrophages and Talaromyces marneffei induces exosomes...