Semi-automated RNA Isolation from Tempus Blood RNA Tubes Using the Magcore Plus II Instrument [0.03%]
使用MagCore Plus II仪器对Tempus血液RNA管进行半自动化RNA提取
Marta Černá,Barbora Šťastná,Pavel Pešek et al.
Marta Černá et al.
High-throughput, precise and cost-effective isolation of high-quality RNA is essential for the growing number of RNA-based next-generation sequencing (NGS) analyses. Manual RNA isolation provides sufficient quality but requires significant ...
Exploring the Clinical Significance and Mechanistic Role of the LINC00487/hsa-miR-663b Axis in Cell Line Models of Acute Lung Injury [0.03%]
探究LINC00487/hsa-miR-663b轴在急性肺损伤细胞系模型中的临床意义及作用机制
Xixiang Yan,Ziqi Xie,Xiaoye Zheng et al.
Xixiang Yan et al.
Acute lung injury (ALI) is a serious lung disease that tends to progress to acute respiratory distress syndrome (ARDS). This study was aimed to seek new biomarkers of ALI to provide a basis for monitoring the progress of ALI in time. A huma...
Motaz Fadul,Saleh Baeesa,Alaa Alkhotani et al.
Motaz Fadul et al.
Medulloblastoma (MB) in children is associated with distinct molecular subgroups, reflecting substantial biological heterogeneity. The presence of isocitrate dehydrogenase 1 (IDH1) and IDH2 mutations in paediatric MB has been rarely reporte...
miR-296-3p Controls Osteogenic Proliferation and Differentiation by Targeting ICAT and Is Involved in Fracture Healing [0.03%]
微RNA-296通过靶向ICAT控制骨形成增殖和分化并参与骨折愈合
Feng Xu,Kun Huang,Wenjun Ji et al.
Feng Xu et al.
Fragility fractures have been a cause for concern because of their high incidence. For the prevention and treatment of osteoporotic fractures, it is important to understand how to promote bone formation and increase bone mass. This study in...
Petr Janec,Jana Dorňáková,Jan Živný et al.
Petr Janec et al.
The endothelium plays a crucial role in maintaining vascular homeostasis. Inflammation is initiated by activation of endothelial cells, which results in endothelial dysfunction. Dysfunction of the endothelium can have significant consequenc...
Breast Milk as a Source of Prebiotic Human Milk Oligosaccharides and Bacteria from the Lactobacillaceae Family [0.03%]
人乳低聚糖和来自乳杆菌科的细菌作为母乳来源
Kataryzna Łubiech,Magdalena Twarużek,Elena Sinkiewicz-Darol et al.
Kataryzna Łubiech et al.
Breast milk, as the optimal food for infants and young children, contains all the components necessary for proper growth and development. It is a rich source of both essential nutrients and biologically active factors, making breast milk a ...
miR-4478 Promotes Ferroptosis of Nucleus Pulposus Cells through Targeting SLC7A11 to Induce IVDD [0.03%]
miR-4478通过靶向SLC7A11促进椎间盘细胞铁死亡诱导IVDD
Dongliang Gong,Long Jia,Yuhang Wang et al.
Dongliang Gong et al.
Nucleus pulposus cells (NPC) are important for the development of intervertebral disc degeneration (IVDD). miR-4478 can aggravate IVDD, but whether it can aggravate IVDD by regulating ferroptosis in NPC remains unclear. The optimal level of...
Clinical Value and Regulatory Mechanism of miR-767-5p in Colorectal Cancer [0.03%]
miR-767-5p在结直肠癌中的临床价值及调控机制
Ping Lin,Xiuju Qin,Caiyun Yi et al.
Ping Lin et al.
The poor prognosis of colorectal cancer (CRC) contributes to a yearly increase in CRC mortality, while microRNAs (miRNAs) were found to play a regulatory function in diversiform cancers, including CRC. The objective of this research was to ...
The Potential Inflammatory Role of IL-6 Signalling in Perturbing the Energy Metabolism Function by Stimulating the Akt-mTOR Pathway in Jurkat T Cells [0.03%]
白细胞介素6信号通过刺激Akt-mTOR途径扰乱能量代谢功能的潜在炎症作用 механизма Akt-mTOR в нарушении энергетического метаболизма путем стимулирования иммунокомплементарного пути IL-6 в клетках юрката
Abdullah Alghamdi,Mohammed Alissa
Abdullah Alghamdi
Numerous studies have reported that increased interleukin 6 (IL-6) and soluble IL-6 receptor (sIL-6) levels induce inflammatory conditions. However, the exact mechanisms by which IL-6 drives inflammatory conditions remain unclear. Therefore...
Selected Genetic Characteristics of the Vietnamese Minority Living in the Czech Republic [0.03%]
居住在捷克共和国的越南少数族裔所选择的遗传特征
Khanh Ha Pham,Jaroslav A Hubáček
Khanh Ha Pham
The aim of this study was to analyse the allelic distribution of selected genes in the Czech and Vietnamese populations. We analysed samples from 94 Vietnamese volunteers and 2,859 Czech population-based subjects (2,559 from the Czechs post...