Breast Milk as a Source of Prebiotic Human Milk Oligosaccharides and Bacteria from the Lactobacillaceae Family [0.03%]
人乳低聚糖和来自乳杆菌科的细菌作为母乳来源
Kataryzna Łubiech,Magdalena Twarużek,Elena Sinkiewicz-Darol et al.
Kataryzna Łubiech et al.
Breast milk, as the optimal food for infants and young children, contains all the components necessary for proper growth and development. It is a rich source of both essential nutrients and biologically active factors, making breast milk a ...
miR-4478 Promotes Ferroptosis of Nucleus Pulposus Cells through Targeting SLC7A11 to Induce IVDD [0.03%]
miR-4478通过靶向SLC7A11促进椎间盘细胞铁死亡诱导IVDD
Dongliang Gong,Long Jia,Yuhang Wang et al.
Dongliang Gong et al.
Nucleus pulposus cells (NPC) are important for the development of intervertebral disc degeneration (IVDD). miR-4478 can aggravate IVDD, but whether it can aggravate IVDD by regulating ferroptosis in NPC remains unclear. The optimal level of...
Clinical Value and Regulatory Mechanism of miR-767-5p in Colorectal Cancer [0.03%]
miR-767-5p在结直肠癌中的临床价值及调控机制
Ping Lin,Xiuju Qin,Caiyun Yi et al.
Ping Lin et al.
The poor prognosis of colorectal cancer (CRC) contributes to a yearly increase in CRC mortality, while microRNAs (miRNAs) were found to play a regulatory function in diversiform cancers, including CRC. The objective of this research was to ...
The Potential Inflammatory Role of IL-6 Signalling in Perturbing the Energy Metabolism Function by Stimulating the Akt-mTOR Pathway in Jurkat T Cells [0.03%]
白细胞介素6信号通过刺激Akt-mTOR途径扰乱能量代谢功能的潜在炎症作用 механизма Akt-mTOR в нарушении энергетического метаболизма путем стимулирования иммунокомплементарного пути IL-6 в клетках юрката
Abdullah Alghamdi,Mohammed Alissa
Abdullah Alghamdi
Numerous studies have reported that increased interleukin 6 (IL-6) and soluble IL-6 receptor (sIL-6) levels induce inflammatory conditions. However, the exact mechanisms by which IL-6 drives inflammatory conditions remain unclear. Therefore...
Selected Genetic Characteristics of the Vietnamese Minority Living in the Czech Republic [0.03%]
居住在捷克共和国的越南少数族裔所选择的遗传特征
Khanh Ha Pham,Jaroslav A Hubáček
Khanh Ha Pham
The aim of this study was to analyse the allelic distribution of selected genes in the Czech and Vietnamese populations. We analysed samples from 94 Vietnamese volunteers and 2,859 Czech population-based subjects (2,559 from the Czechs post...
Markéta Janatová,Marianna Borecká,Petra Zemánková et al.
Markéta Janatová et al.
Male breast cancer (mBC) is a rare cancer diagnosis that constitutes less than 1 % of all breast cancer cases globally. Genetic factors play an important role in the mBC risk. Germline pathogenic variants (PVs) in cancer predisposition gene...
A Short Retrospective Cytometric Note on Myeloblasts in Patients Suffering from Acute Myeloblastic Leukaemia, Myelodysplastic Syndrome and Chronic Myelocytic Leukaemia: Myeloblasts with a Narrow Cytoplasm without Azurophilic Granules Are Less Differentiated Committed Progenitor Stem Cells [0.03%]
有关急性髓系白血病、骨髓增生异常综合征和慢性粒细胞白血病患者的原始粒细胞的流式细胞术简短回顾：无嗜天青颗粒的狭细胞质的原始粒细胞是分化的承诺祖细胞干细胞
Karel Smetana,Hana Klamová,Radka Šimečková et al.
Karel Smetana et al.
The maximal nuclear and cell body diameters of leukaemic agranular myeloblasts ("type 1" without azurophilic granules) were measured in bone marrow smears of patients suffering from acute myeloblastic leukaemia with minimal differentiation ...
Down-regulation of lncRNA EMX2OS Is Associated with the Prognosis of Patients with Cervical Squamous Cell Carcinoma and Regulates Tumour Cell Progression via miR-574-5p [0.03%]
低表达长链非编码RNA EMX2OS与宫颈鳞状细胞癌患者的预后有关并通过miR-574-5p调控肿瘤细胞的发展
Quan Cheng,Ting Hu,Wenhui Zhang et al.
Quan Cheng et al.
Cervical squamous cell carcinoma (CSCC) represents a malignant subtype of cervical cancer. Identification of novel biomarkers for CSCC development could enhance therapeutic efficiency and improve the patients' outcomes. This study focused o...
Serum Biomarkers in Diagnosis and Clinical Management of Inflammatory Bowel Disease: Anything New on the Horizon? [0.03%]
炎症性肠病诊断和临床治疗中的血清生物标志物：有什么新进展？
Juraj Ondriš,Rastislav Husťak,Juraj Ďurina et al.
Juraj Ondriš et al.
Persistent inflammation in inflammatory bowel disease (IBD) leads to progressive damage to the gastrointestinal tract, resulting in potentially severe sequelae. Diagnosis primarily relies on invasive endoscopy and monitoring of faecal calpr...
Jiří Hlušička,Aleš Žák
Jiří Hlušička
The liver is the central organ in lipid metabolism and plays a key role in a variety of biochemical processes. It is involved in lipoprotein synthesis, fatty acid beta oxidation, ketone body production, cholesterol synthesis, bile productio...