Luteoloside Ameliorates Palmitic Acid-Induced in Vitro Model of Non-alcoholic Fatty Liver Disease via Activating STAT3-Triggered Hepatocyte Regeneration [0.03%]
金丝桃苷通过激活STAT3诱导的肝细胞再生来改善棕榈酸诱导的非酒精性脂肪肝病体外模型
Y X Zhu,L Zhu,Y F Chen et al.
Y X Zhu et al.
Luteoloside (Lute), a bioactive natural ingredient, widely exists in nature and possesses hepatoprotective and hepatocyte proliferation-promoting properties. This study aimed to investigate whether Lute could counteract non-alcoholic fatty ...
Insulin-Like Growth Factor Binding Protein 5: an Important Regulator of Early Osteogenic Differentiation of hMSCs [0.03%]
胰岛素样生长因子结合蛋白5：人骨髓间充质干细胞早期成骨分化的关键调控因素
Z M Zhang,L Min,D L Jiang et al.
Z M Zhang et al.
Insulin-like growth factor binding protein 5 (IGFBP5) is broadly bioactive, but its role in osteogenic differentiation of human bone marrow-derived mesenchymal stem cells (hMSCs) remains to be clarified. Here, we demonstrated that IGFBP5 ex...
Asiatic Acid Induces Mitochondrial Apoptosis via Inhibition of JAK2/STAT3 Signalling Pathway in Human Osteosarcoma [0.03%]
没食子酸通过抑制JAK2/STAT3信号通路诱导人成骨肉瘤细胞线粒体凋亡作用机制研究
B F Yan,X Chen,J Liu et al.
B F Yan et al.
Osteosarcoma (OS), a severe malignant bone tumour, usually occurs in adolescents and children and has a poor prognosis. Asiatic acid (AA), an active component isolated from Centella asiatica (L.) Urb., exhibits appreciable anti-oxidant and ...
Inhibition of SRSF3 Alleviates Proliferation and Migration of Gastric Cancer Cells by Regulating the PI3K/AKT/mTOR Signalling Pathway [0.03%]
通过调节PI3K/AKT/mTOR信号通路抑制SRSF3可缓解胃癌细胞增殖和迁移
J Xie,Y Sun,Q Xu
J Xie
This study was aimed to investigate the impact of serine/arginine-rich splicing factor 3 (SRSF3) on the proliferation and migration of gastric cancer (GC) cells. SRSF3 levels in GC tissues and cell lines were measured by Western blotting. F...
Hypoxia-Induced LXRα Contributes to the Migration and Invasion of Gastric Cancer Cells [0.03%]
缺氧诱导的LXRα促进胃癌细胞迁移侵袭
R Guo,B Yang
R Guo
Gastric cancer is characterized by the presence of high invasion ability, hypoxia and chemoresistance. Previous studies reported that liver X receptor α (LXRα) was involved in epithelial-mesenchymal transition (EMT) of gastric cancer cell...
A G Kovalčíková,N Ivašková,J Hodosy et al.
A G Kovalčíková et al.
Salivary urea is studied as a non-invasive alternative for screening and monitoring of renal diseases. Its high variability prevents a wider clinical use. Animal experiments are needed to identify factors affecting this marker. The aim of t...
YBX1 Protects against Apoptosis Induced by Oxygen-Glucose Deprivation/Reoxygenation in PC12 Cells via Activation of the AKT/GSK3β Pathway [0.03%]
YBX1通过激活AKT/GSK3β信号通路保护氧糖剥夺/复氧诱导的PC12细胞凋亡
T Tuerxun,X Li,F Lou et al.
T Tuerxun et al.
Reperfusion therapies for ischaemic stroke can induce secondary injury accompanied by neuronal death. The Y-box binding protein 1 (YBX1), an oncoprotein, is critical for regulating tumour cell proliferation and apoptosis. Thus, we wanted to...
Metabolic Effects of a Hydrophobic Alginate Derivative and Tetrahydrolipstatin in Rats Fed a Diet Supplemented with Palm Fat and Cholesterol [0.03%]
羟基褐藻酸盐衍生物及四氢脂立普汀对饲以棕榈油和胆固醇大鼠的代谢效应
M Marounek,Z Volek,T Taubner et al.
M Marounek et al.
The effects of octadecylamide of alginic acid (amidated alginate) and tetrahydrolipstatin on serum and hepatic cholesterol, and the faecal output of fat and sterols, were investigated in rats. Amidated alginate is a sorbent of lipids, tetra...
Scanning Electron Microscopy and Macroscopic Examination of Prematurely Erupted Teeth in Preterm Infants [0.03%]
早产儿早期萌出牙齿的扫描电子显微镜和宏观检查
V Merglova,A Nemeckova,L Hauler et al.
V Merglova et al.
Prematurely erupted teeth are rare in fullterm neonates and extremely rare in prematurely delivered infants. The aim of this study was to present macroscopic and scanning electron microscopy (SEM) investigations of prematurely erupted prima...
Latent Defect in Haematopoiesis of UBC-GFP Mice Sheds Light on the Lymphoid Developmental Potential of Haematopoietic Stem Cells [0.03%]
UBC-GFP小鼠造血的潜在缺陷揭示了造血干细胞淋巴系发育潜能
E Nečas,K Faltusová,C-L Chen
E Nečas
Editorial
Folia biologica. 2021;67(4):135. DOI: 2021