G Cunnane,J D O&#x;Duffy
G Cunnane
Lilach Ben Dror,Eilon Barnea,Ilan Beer et al.
Lilach Ben Dror et al.
Objective: The HLA-B27 allele is strongly associated with the group of inflammatory diseases known as the spondylarthritides (SpA). The aim of this study was to perform a large-scale, direct biochemical analysis of the HL...
Does the sTNFRII biomarker mainly detect subclinical or preclinical rheumatoid arthritis? [0.03%]
sTNFRII生物标志物主要检测亚临床还是前期类风湿关节炎？
Alfonse T Masi,Jean C Aldag
Alfonse T Masi
Periarticular bone structure in rheumatoid arthritis patients and healthy individuals assessed by high-resolution computed tomography [0.03%]
高分辨率CT评估类风湿关节炎患者和健康人的骨性关节结构
Christian M Stach,Michael Bäuerle,Matthias Englbrecht et al.
Christian M Stach et al.
Objective: To define the nature of structural bone changes in patients with rheumatoid arthritis (RA) compared with those in healthy individuals by using the novel technique of high-resolution microfocal computed tomograp...
Controlled Clinical Trial
Arthritis and rheumatism. 2010 Feb;62(2):330-9. DOI:10.1002/art.27252 2010
Excessive interleukin-1 signaling determines the development of Th1 and Th17 responses in chronic inflammation [0.03%]
过度的白细胞介素-1信号决定慢性炎症中Th1和Th17反应的发展
Leo A B Joosten
Leo A B Joosten
Association of 25-hydroxyvitamin D with prevalent osteoarthritis of the hip in elderly men: the osteoporotic fractures in men study [0.03%]
老年男性股骨骨性关节炎与25-羟基维生素D的关联：男性骨折研究
R K Chaganti,N Parimi,P Cawthon et al.
R K Chaganti et al.
Objective: To examine the cross-sectional association of serum levels of 25-hydroxyvitamin D, or 25(OH)D, with prevalent radiographic hip osteoarthritis (OA) in elderly men. ...
Clinical features and outcomes in 348 patients with polyarteritis nodosa: a systematic retrospective study of patients diagnosed between 1963 and 2005 and entered into the French Vasculitis Study Group Database [0.03%]
348例结节性多动脉炎的临床特点和转归——法国血管炎研究组数据库登记（1963年至2005年）患者的系统回顾分析
Christian Pagnoux,Raphaèle Seror,Corneliu Henegar et al.
Christian Pagnoux et al.
Objective: Previous studies of polyarteritis nodosa (PAN) included patients with microscopic polyangiitis, because these entities were not distinguished prior to the Chapel Hill Consensus Conference (CHCC). This study was...
Activation of AMP-activated protein kinase by adiponectin rescues salivary gland epithelial cells from spontaneous and interferon-gamma-induced apoptosis [0.03%]
脂联素活化AMP激活的蛋白激酶可抢救唾液腺上皮细胞免受自发和γ干扰素诱导的凋亡作用
Stergios Katsiougiannis,Roxane Tenta,Fotini N Skopouli
Stergios Katsiougiannis
Objective: Primary Sjögren's syndrome (SS) is an autoimmune disease characterized by lymphocytic infiltrates associated with destruction of salivary gland epithelial cells (SGECs) induced mainly by apoptosis. Adiponectin...
Smoking increases rheumatoid arthritis susceptibility in individuals carrying the HLA-DRB1 shared epitope, regardless of rheumatoid factor or anti-cyclic citrullinated peptide antibody status [0.03%]
吸烟通过人类白细胞抗原增加携带共享表位个体的类风湿关节炎的发病风险，无论类风湿因子或抗环瓜氨酸肽抗体状态如何
So-Young Bang,Kyoung-Ho Lee,Soo-Kyung Cho et al.
So-Young Bang et al.
Objective: Smoking is associated with rheumatoid arthritis (RA) in individuals with the HLA-DRB1 shared epitope (SE). SE alleles have been shown to be predominantly associated with anti-cyclic citrullinated peptide (anti-...
Tumor necrosis factor neutralization results in disseminated disease in acute and latent Mycobacterium tuberculosis infection with normal granuloma structure in a cynomolgus macaque model [0.03%]
肿瘤坏死因子的中和作用导致了急性期和潜伏期结核分枝杆菌感染的弥散性疾病，而恒河猴模型中的肉芽肿结构正常
Philana Ling Lin,Amy Myers,Le&#x;Kneitah Smith et al.
Philana Ling Lin et al.
Objective: An increased risk of tuberculosis has been documented in humans treated with tumor necrosis factor alpha (TNFalpha)-neutralizing agents. In murine models, impaired signaling by TNF causes exacerbation of both a...